Alnylam Pharmaceuticals · 4 days ago
Sr Manager, Biostatistics
Cambridge, MA
Full-time
Onsite
Mid, Senior Level
$157K/yr - $213K/yr
3+ years expAlnylam Pharmaceuticals is a leader in RNAi therapeutics, committed to transforming lives with innovative science. The Senior Manager, Biostatistics will lead statistical activities supporting Medical Affairs, focusing on evidence generation, study design, and data analysis.
BiotechnologyHealth CareMedicalPharmaceuticalTherapeutics
Responsibilities
Leads statistical support for post approval value evidence generation and reimbursement submissions
Conducts post hoc analysis to support publications and presentations
Reviews and authors abstract, manuscript, regulatory documents
Collaborates with cross-functional team to support observational studies
Develops statistical sections of study protocols and statistical analysis plans
Collaborates with Data Management and Medical Research on design of eCRFs
Provides statistical guidance on conduct of ongoing studies
Accountable for the collaboration with Statistical Programming to implement statistical analysis of all clinical trial, registry, observational and non-interventional data supporting Medical Affairs needs
Contributes to observational study reports and regulatory documents, e.g., DSURs, briefing documents, etc
Contributes to scientific articles, summarizing data collected in Alnylam studies
Participates in other activities and meetings to support Biostatistics and the Medical Affairs team as needed
Qualification
Required
PhD in Biostatistics, Statistics, or equivalent with at least 3 years pharmaceutical biostatistics experience; or MS with at least 5 years' relevant experience
Excellent written and oral communication and presentation skills
Extensive experience and strong hand-on skills programming in SAS
Extensive experiences working on data analysis with clinical studies database
Experience working on post-approval observational and clinical studies
Understanding of ICH GCP as well as general knowledge of industry practices and standards
Experiences in R programming language and other statistical software
Experience with CDISC, including SDTM, ADaM, CDASH
Benefits
Comprehensive benefits including medical, dental, and vision coverage
Life and disability insurance
A lifestyle reimbursement program
Flexible spending and health savings accounts
A 401(k) with a generous company match
Paid time off
Wellness days
Holidays
Two company-wide recharge breaks
Generous family resources and leave
Company
Alnylam Pharmaceuticals
Alnylam Pharmaceuticals is a biopharmaceutical company focused on the discovery, development and commercialization.
1001-5000 employees
H1B Sponsorship
Alnylam Pharmaceuticals has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2022 (18)
2021 (19)
2020 (7)
Funding
Current Stage
Public CompanyTotal Funding
$4.55BKey Investors
Blackstone Life SciencesBlackstone CreditRegeneron
2025-09-09Post Ipo Debt· $661.25M
2022-09-12Post Ipo Debt· $900M
2022-03-04IPO
Leadership Team
Yvonne Greenstreet
Chief Executive Officer
Jeff Poulton
Chief Financial Officer
Recent News
Clinical Trials Arena
2026-01-16
Longevity.Technology
2026-01-14
2026-01-13
Company data provided by crunchbase