Bausch Health Companies Inc. · 1 day ago
Senior Principal Scientist, Clinical Pharmacology
Bridgewater, NJ
Full-time
Onsite
Senior Level, Lead/Staff
$167K/yr - $229K/yr
5+ years expBausch Health Companies Inc. is a global diversified pharmaceutical company dedicated to improving health outcomes for patients. The Senior Principal Scientist will lead the strategy, execution, and reporting of Clinical Pharmacology studies, integrating various scientific disciplines to support drug development and regulatory submissions.
BiotechnologyHealth CareMedicalPharmaceutical
Responsibilities
Lead and support the design, conduct, interpretation and reporting of clinical pharmacology studies, including but not limited to PK, food effect, drug-drug interactions, TQT, and hepatic/renal impairment studies
Lead pharmacokinetics (PK) and/or pharmacodynamics (PD) aspects of study plans and integrate quantitative approaches into drug development projects
Conduct exploratory PK and pharmacometrics analyses such as Physiologically-based Pharmacokinetic (PBPK) or population PK (popPK) modeling to support therapeutic decisions, trial design, dosing strategies, and post-approval changes
Manage CRO/vendors to execute PK/PD and pharmacometrics deliverables for regulatory submissions
Represent the Clinical Pharmacology function in cross functional teams including Project Management, Clinical Operations, Clinical/Medical Affairs, Biostatistics, Regulatory Affairs and Medical Writing
Collaborate closely with the clinical project team to manage Phase I-III and post-marketing studies
Other responsibilities may include planning, writing, and reviewing relevant sections of clinical documents such as study protocols, analysis plans, reports, and regulatory documents (IBs, INDs, NDAs, etc.)
Maintain awareness of emerging literature and science in computational approaches and applications as well as relevant regulatory guidances
Qualification
Required
Ph.D. in Pharmacokinetics/Pharmacodynamics, Clinical Pharmacology, Pharmacometrics, Pharmacology, or related field, or Pharm.D. with demonstrated clinical pharmacology and pharmacokinetic training and experience required. M.S. degrees with significant applicable experience will also be considered
PhD with minimum of 5 years of experience in clinical pharmacology and drug development in the pharmaceutical industry; Masters degree with 10 years
Experience in applying clinical pharmacology, PK, PD, and pharmacometrics principles within drug development teams
Hands-on experience with non-compartmental and compartmental PK/PD analysis using Phoenix WinNonlin
Hands-on experience with one or more pharmacometrics analysis, e.g., PBPK modeling, population PK (popPK) modeling, exposure-response (E-R) analysis and pharmacometrics software platforms (e.g., Simcyp, GastroPlus, NONMEM, etc.)
Familiarity with LC/MS-based bioanalysis to support in vivo PK, toxicity, and PK/PD studies
Ability to communicate effectively and with confidence, and work in a matrix environment
Preferred
Previous experience in gastroenterology, dermatology and/or inflammatory indications preferred
Benefits
Comprehensive Medical (includes Prescription Drug)
Dental
Vision
Flexible Spending Accounts
401(k) with matching company contribution
Discretionary time off
Paid sick time
Stock purchase plan
Tuition reimbursement
Parental leave
Short-term and long-term disability
Life insurance
Accidental death & dismemberment insurance
Paid holidays
Employee referral bonuses
Employee discounts
Company
Bausch Health Companies Inc.
Bausch Health Companies Inc.
5001-10000 employees
H1B Sponsorship
Bausch Health Companies Inc. has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (8)
2024 (7)
2023 (4)
2022 (13)
2021 (4)
2020 (5)
Funding
Current Stage
Public CompanyTotal Funding
$7.4BKey Investors
Kohlberg Kravis Roberts
2025-05-21Post Ipo Debt· $2.52B
2025-03-25Post Ipo Debt· $3.08B
2023-07-07Post Ipo Debt· $600M
Leadership Team
Thomas J. Appio
Chief Executive Officer
Graham Jackson
SVP, Chief Quality Officer & Global Head Technical Operations
Recent News
2026-01-05
2025-12-24
2025-12-09
Company data provided by crunchbase