Vertex Pharmaceuticals · 21 hours ago
Protein Science Principal Research Associate
Seattle, WA
Full-time
Onsite
Senior Level, Lead/Staff
$88K/yr - $132K/yr
3+ years expVertex Pharmaceuticals is a global biotechnology company that invests in scientific innovation. They are seeking a Protein Science Principal Research Associate to provide laboratory support in the advancement of their Protein Engineering pipeline, focusing on cloning workflows, yeast transformation, and protein characterization.
BiotechnologyHealth CareMedicalPharmaceutical
Responsibilities
Execute and troubleshoot molecular cloning workflows spanning plasmid assembly to plasmid preparation at mini- and midi- scales
Perform small-scale yeast transformations and culturing
Support characterization of yeast displayed proteins by flow cytometry
Support large-scale yeast transformations with DNA libraries
Support lab operations and equipment purchasing if needed
Perform high-throughput purification of proteins and protein-analytics using UV-Vis Spectroscopy, analytical SEC (UPLC-HPLC through Empower software), endotoxin tests, SDS-PAGE, and western blotting
Manage protein inventory in the protein database and Protein Science freezers
Provide protein dilutions and protein aliquots to immunology group and pharmacology group as needed
Deliver verbal and presentation updates on cloning, expression, purification and analytics to the Protein Science Team
Ensure that a complete and timely record of experiments, constructs, plasmid preps is maintained in both the protein database and electronic lab notebooks
Qualification
Required
Master's Degree (or equivalent degree) in cellular biology, biochemistry, biophysics, or bio/chemical engineering and 3+ years of relevant industry experience, or
Bachelor's Degree (or equivalent degree) in cellular biology, biochemistry, biophysics, or bio/chemical engineering and 6 + years of relevant industry experience
Experience using electronic lab notebooks, cloning software such as snap gene
Experience in working in a highly collaborative laboratory which is timeline-driven and result orientated team is a must
Experience in mammalian cell culture work to transiently express and purify recombinant proteins is a must
Expertise in molecular biology techniques such as PCR, DNA cloning is a must
Benefits
Medical, dental and vision benefits
Generous paid time off (including a week-long company shutdown in the Summer and the Winter)
Educational assistance programs including student loan repayment
A generous commuting subsidy
Matching charitable donations
401(k)
Company
Vertex Pharmaceuticals
Vertex Pharmaceuticals is focused on the discovery and development of small molecule drugs for the treatment of serious diseases.
5001-10000 employees
H1B Sponsorship
Vertex Pharmaceuticals has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (188)
2024 (150)
2023 (111)
2022 (164)
2021 (112)
2020 (80)
Funding
Current Stage
Public CompanyTotal Funding
$657.31MKey Investors
Janssen Belgium
2024-07-10Post Ipo Secondary· $1.11M
2022-05-17Post Ipo Equity· $50M
2009-12-03Post Ipo Equity· $443M
Leadership Team
Reshma Kewalramani
CEO and President
Nina Devlin
Senior Vice President, Chief Communications Officer
Recent News
2026-01-13
2026-01-12
Company data provided by crunchbase