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R&D Partners · 8 hours ago

Senior Systems Engineer (PCR / Library Prep)

Santa Clara, CA

Contract

Onsite

Mid, Senior Level

$116K/yr - $145K/yr

5+ years exp

R&D Partners is a global functional service provider specializing in scientific, clinical research, and engineering. They are hiring a Senior Systems Engineer to support the Next Generation Sequencing (NGS) products, contributing to feasibility, development, customer support, and integration of end-to-end NGS solutions while maintaining detailed documentation throughout the research and development phases.

Staffing Agency

Responsibilities

Perform a variety of sample prep, library, or sequencing and sequencing related experiments on a daily basis; help to analyze and interpret the data

General support of diverse research and development activities

Customer support activities such as monitoring runs, documenting and communicating defects, and following escalation paths to resolve customer issues

Contribute to the platform verification team as a member by executing, analyzing, and interpreting the results of platform verification studies

Perform all work using best laboratory practices and maintain a well-organized and concise record of work performed and progress made

Assist engineers with hardware design through testing subcomponents

Analyze data, derive conclusions, document findings, write SOPs and prepare reports for sharing within and between R&D groups

Setup strong experimental designs while working independently

Troubleshoot instrument failures and seek out specialized help as needed

Develop and deploy a wide range of technologies, including sample extraction, library prep, and sequencing

Develop, execute, and document test cases for verification and validation. Ensures complete and comprehensive coverage of requirements in the test campaigns

Customer support through monitoring of runs, early morning meetings to discuss defects, results and progress, QC of reagents and configuration used for customer, possible travel to customer sites

Support of instrument fleet to learn troubleshooting techniques as needed to assist R&D and to support customers

Perform system integration and testing activities and verify system performance through simulation, tests, and measurements. Assess results for applicability, validity, and conformance to product requirements

Work independently with general management direction to drive product development and collaborations to identify opportunities for continuous improvement

Keep supervisor/project leader informed of project status, particularly of significant findings and results in critical problem areas

Qualification

DNA sequencingPCRNGS workflowMATLABPythonStatistical toolsMolecular BiologyCustomer supportTroubleshootingDocumentation

Required

B.S. or M.S. or PhD degree in the science/chemistry/engineering required and 5+ years of experience in biotechnology or medical device development

3+ years of hands-on experience with DNA sequencing such as raw sample preparation, nucleic acid extraction, library preparation, and NGS sequencing

Previous laboratory experience required

Familiarity with MATLAB, GIT, Python or similar tools for data analysis and/or automation

Previous experience with PCR required; Experience with a variety of laboratory devices and instrumentation, including PCR and automation

Strong understanding of DNA & molecular Biology

Proven hands-on troubleshooting experience and skills in wet bench workflows on NGS platform

Experience with statistical tools (e.g. Python/JMP for regression analysis, ANOVA) and Design of Experiments methodology, application of statistical process control is essential