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Fortrea · 8 hours ago

Clinical Bioinformatics Scientist III

United States

Full-time

Remote

Mid, Senior Level

$110K/yr - $140K/yr

4+ years exp

Labcorp is dedicated to bringing comprehensive genetic information into mainstream medicine to improve healthcare for billions of people. The Clinical Bioinformatics Scientist III will evaluate clinically reportable variants, monitor data quality, and troubleshoot quality control failures, all of which directly impact patient results.

Clinical TrialsHealth Care

No H1B

Responsibilities

Review and assess the veracity of specific genetic variants (SNVs and CNVs) in NGS or WGS data flagged for manual intervention. This process entails making decisions that will determine if a variant is reported to a patient or not

Review results from confirmatory assays that corroborate or refute calls made in the primary assay. This can lead to contradictory results between assays where the scientist will need to make the final decision

Troubleshoot quality control anomalies generated by automated pipelines at the sample and/or batch level

Triage stuck samples, variants, and reports

Support other production duties like requests from other teams, production on-call shifts, and program development

Collaborate with other teams such as bioinformatics, automation, engineering, clinical genomics, laboratory scientists, laboratory directors, and research scientists in a cross-functional manner

Qualification

NGS data analysisGenetics knowledgeVariant calling toolsGenome browsersNGS wet lab protocolsProgramming languagesLIMSVersion control systemsProject management softwareCommunication skills

Required

Strong knowledge of genetics

Experience with NGS data analysis in either an academic or industry environment

Familiarity with IGV or other genome browsers

Knowledge of common NGS alignment, variant calling, and visualization tools

Familiarity and/or hands-on experience with NGS wet lab protocols, preferably in a production setting but academic knowledge may be sufficient

Excellent written and verbal communication skills

Bachelor's degree in a biological field (e.g., biology, microbiology, genetics, genomics, bioinformatics, biochemistry, etc.) and four years of relevant professional experience

Master's Degree in a biological field (e.g., biology, microbiology, genomics, bioinformatics, biochemistry, etc.) and two years of relevant professional experience