Genentech · 6 hours ago
Senior Principal DSX Data Scientist
Boston, MA
Full-time
Onsite
Senior Level, Lead/Staff
$189K/yr - $352K/yr
8+ years expGenentech is dedicated to innovating healthcare solutions and ensuring access to healthcare for everyone. The Senior Principal DSX Data Scientist in the Analytical Data Science team is responsible for developing scalable tools and workflows to enhance statistical computing, collaborating with various stakeholders to streamline evidence generation and decision-making in clinical development.
BiotechnologyLife ScienceManufacturing
Responsibilities
You provide strategic and technical leadership in the design and evolution of Roche’s next-generation statistical computing platforms, ensuring they meet the future needs of PDD and the broader organization
You anticipate emerging industry trends, technologies, and regulatory shifts, and translate them into forward-looking data science capabilities, frameworks, and standards
You lead large-scale, cross-functional initiatives that redefine how clinical, operational, or real-world data are processed, visualized, and interpreted for decision-making
You serve as a senior technical advisor to platform owners, programming and statistical leadership, and governance teams on complex topics involving infrastructure, automation, and scientific computing
You guide technical vision, architectural decisions, and resource planning for high-impact tooling and infrastructure projects across DSX
You resolve complex, system-level challenges across disciplines by applying deep scientific computing expertise and systems thinking
You influence internal policy and development standards, and drive adoption of best practices that scale across teams, functions, and geographies
You communicate complex technical ideas clearly to senior-level stakeholders and shape decisions on investment, tooling strategy, and portfolio priorities
You foster a culture of technical excellence, collaboration, and innovation through mentorship, internal community building, and knowledge sharing
Qualification
Required
You hold a PhD or Master's degree in Computer Science, Data Science, Statistics, Bioinformatics, Engineering, or a related quantitative field
You have a minimum of 8 years of experience in data science, statistical computing, or platform development, with a demonstrated track record of impact at organizational or cross-functional levels
You are a recognized expert in building and scaling scientific or statistical software systems, with deep understanding of clinical research environments and regulatory implications
You bring expertise in multiple programming environments (e.g., Python, R) and development practices for reproducible, compliant, and high-performance computing
You have demonstrated leadership of major programs or cross-functional initiatives with technical complexity and strategic significance
You demonstrate capacity for independent thinking and ability to make decisions based upon sound principles
You bring excellent strategic agility including problem-solving and critical thinking skills, and agility that extends beyond the technical domain
You demonstrate respect for cultural differences when interacting with colleagues in the global workplace
You have excellent verbal and written communication skills, including the ability to influence senior stakeholders and explain technical strategy with clarity and confidence
You have proven experience leading global, cross-functional projects or workstreams, demonstrating effective coordination across time zones and diverse stakeholder groups
Preferred
Experience shaping the architecture and long-term roadmap of enterprise-scale data science platforms or statistical computing environments
Demonstrated ability to influence regulatory and quality frameworks in the context of digital and analytical tools
Strategic understanding of healthcare data ecosystems, including real-world data, translational pipelines, and high-dimensional data integration
Proven ability to drive tool adoption and cultural change through technical leadership, stakeholder engagement, and thoughtful design
Engagement with external scientific or developer communities (e.g., open-source contributions, industry consortia, conference presentations)
Experience guiding investment and resource decisions for high-impact tooling or analytics initiatives
Ability to synthesize organizational priorities and translate them into impactful, technically sound solutions at scale
Benefits
A discretionary annual bonus may be available based on individual and Company performance.
This position also qualifies for the benefits detailed at the link provided below.
Company
Genentech
Genentech is a biotechnology research company that specializes in genetic testing and personalized medicines.
10001+ employees
H1B Sponsorship
Genentech has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (167)
2024 (148)
2023 (150)
2022 (178)
2021 (121)
2020 (158)
Funding
Current Stage
Public CompanyTotal Funding
unknown2009-03-26Acquired
1999-07-20IPO
1976-01-01Series Unknown
Leadership Team
Ashley Magargee
Chief Executive Officer
Michael Laird
Vice President, Global MSAT Drug Substance Biologics Technology and Commercial Products Support
Recent News
2026-01-07
MarketScreener
2026-01-06
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