SystImmune · 23 hours ago
Research Associate I/II – Clinical Pathology/IHC Biomarker Development
Redmond, WA
Full-time
Onsite
Entry, Mid Level
$60K/yr - $80K/yr
1+ years expSystImmune is a leading and well-funded clinical-stage biopharmaceutical company specializing in developing innovative cancer treatments. They are seeking a highly organized and detail-oriented Research Associate I/II to support the development, optimization, and validation of immunohistochemistry (IHC) assays, contributing to early-stage biomarker programs for clinical trials.
BiopharmaBiotechnologyProfessional Services
Responsibilities
Perform tissue sectioning of FFPE blocks
Route and support H&E staining workflows
Perform routine IHC staining on FFPE tissue specimens using automated platforms (e.g., Ventana, Leica)
Conduct antibody titrations, protocol optimization, slide preparation, and quality control checks
Assist in generating feasibility, optimization, and analytical validation data for emerging CDx assays
Manage tissue samples and associated documentation
Prepare tissue sections, including slide cutting, baking, antigen retrieval, and reagent preparation
Maintain sample integrity, traceability, and documentation in compliance with quality system requirements
Support tissue handling workflows (blocks, slides, labeling, storage) within GLP or CLIA/CAP environments
Accurately record experimental data in ELN and/or LIMS systems
Capture high-quality slide images and perform basic image analysis
Assist with slide scoring preparation and data summaries
Summarize experimental findings for internal meetings and assay development reviews
Operate, calibrate, and troubleshoot automated IHC staining platforms and related laboratory equipment
Perform routine instrument maintenance and maintain equipment logs per laboratory quality systems
Monitor and manage inventory of reagents, antibodies, controls, and consumables
Collaborate with scientists, pathologists, QA, and clinical development teams on assay transfer, optimization, and validation activities
Support preparation of study materials, controlled documents, and protocol execution for validation studies
Qualification
Required
BS or MS in Biology, Molecular Biology, Pathology, Biomedical Sciences, or a related field
1–3 years of hands-on experience in histology and/or IHC assay execution within a research or regulated diagnostic laboratory
Experience handling FFPE tissues and operating automated IHC staining platforms
Strong attention to detail with excellent documentation and record-keeping practices
Ability to follow SOPs and work effectively in CLIA-, GxP-, or ISO-regulated environments
Preferred
Experience supporting IHC assay optimization and/or analytical validation studies
Exposure to Akoya platforms and multiplex immunofluorescence projects
Experience with digital pathology, slide scanning, or image analysis tools
Knowledge of antibody characterization and tissue-based biomarker assay development
Benefits
100% paid employee premiums for medical/dental/vision
STD
LTD
401(k) plan with a 50% company match of up to 3%
Vesting schedule of only 5 years
15 PTO days per year
Sick leave
11 paid holidays
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Company
SystImmune
SystImmune is a biotechnology company.
51-200 employees
H1B Sponsorship
SystImmune has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (14)
2023 (1)
2022 (2)
2021 (2)
2020 (1)
Funding
Current Stage
Growth StageLeadership Team
Martin S. Olivo, MD, MSc,
Chief Medical Officer
Recent News
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