Ardelyx, Inc. · 9 hours ago
Senior Infrastructure Engineer I
Waltham, Massachusetts
Full-time
Onsite
Senior Level
$135K/yr - $165K/yr
6+ years expArdelyx, Inc. is a publicly traded commercial biopharmaceutical company focused on developing innovative medicines. The Senior Infrastructure Engineer I is responsible for designing and improving the company's hybrid cloud and on-prem infrastructure, with a strong emphasis on automation and operational efficiency.
BiotechnologyHealth CareMedical
Responsibilities
Lead and mentor junior staff by guiding them in automating routine IT operations and reducing manual, repetitive work
Design, develop, and standardize automation solutions (PowerShell, Python, Bash) for patching, provisioning, monitoring, remediation, and configuration management
Establish best practices, reusable scripts, and runbooks that junior staff can follow to execute infrastructure tasks consistently and safely
Monitor and troubleshoot cloud and on-prem infrastructure for availability, performance, and reliability issues; drive automated detection and remediation where possible
Improve infrastructure performance, scalability, resiliency, and operational efficiency through automation-first design and continuous optimization
Own patching, lifecycle management, and configuration baselines, leveraging automation to ensure compliance and consistency across environments
Partner with Security and Compliance teams to automate vulnerability remediation workflows, including emergency fixes and compensating controls
Contribute to monitoring, alerting, and observability practices with a focus on reducing MTTD/MTTR through automation and self-healing mechanisms
Participate in Change Management activities, ensuring automated changes are tested, documented, and validated post-implementation
Serve as a Tier 3 escalation point and technical role model, coaching junior engineers during incidents and complex infrastructure changes
Qualification
Required
Bachelor's degree in Information Technology, Computer Science, Engineering, or related field with 6 – 8+ years of hands-on infrastructure engineering or systems engineering experience or equivalent experience
Strong operational ownership of on-prem, cloud, and hybrid infrastructure
Proven experience with Windows Server, Active Directory, virtualization, and core networking
Hands-on scripting and automation experience (PowerShell, Python, or Bash)
Experience participating in incident, change, and problem management
Ability to work independently on complex technical issues and mentor junior staff
Strong documentation and cross-team communication skills
Preferred
Relevant certifications preferred (Microsoft, VMware, AWS, Azure, Cisco, FortiNet, PaloAlto, etc.)
Benefits
401(k) plan with generous employer match
12 weeks of paid parental leave
Up to 12 weeks of living organ and bone marrow leave
Equity incentive plans
Health plans (medical, prescription drug, dental, and vision)
Life insurance and disability
Flexible time off
Annual Winter Holiday shut down
At least 11 paid holidays
Company
Ardelyx, Inc.
Ardelyx was founded with a mission to discover, develop and commercialize innovative, first-in-class medicines that meet significant unmet medical needs.
201-500 employees
H1B Sponsorship
Ardelyx, Inc. has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
2024 (1)
2022 (1)
2020 (1)
Funding
Current Stage
Public CompanyTotal Funding
$557.68MKey Investors
HealthCare Royalty PartnersSLR Capital PartnersNew Enterprise Associates
2022-06-30Post Ipo Debt· $20M
2022-02-24Post Ipo Debt· $27.5M
2019-12-12Post Ipo Equity· $125M
Leadership Team
Mike Raab
President & CEO
David Rosenbaum
Chief Development Officer
Recent News
2026-01-09
2026-01-09
2026-01-03
Company data provided by crunchbase