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The Ohio State University Wexner Medical Center · 4 days ago

Research Associate

Columbus, OH

Full-time

Onsite

Entry Level

1+ years exp

The Ohio State University Wexner Medical Center is seeking a highly motivated Research Associate to support experimental research in hematology, leukemia biology, and immuno-oncology. The role involves planning, executing, and managing research projects, as well as conducting various laboratory techniques and analyses related to cancer research.

Health CareHospitalMedical

H1B Sponsor Likely

Responsibilities

Participate in the planning, design, and execution of research projects related to hematopoiesis, leukemia, and tumor immunology, including the development and implementation of experimental goals and study objectives

Execute and manage research projects using molecular and cellular biology techniques, including DNA/RNA extraction, RT-PCR, cloning, bacterial transformation, plasmid isolation, transfection, viral transduction of immune and hematopoietic cells, and CRISPR-Cas9 gene editing

Perform bone marrow– and blood-based assays, including collection, processing, enrichment, and analysis of hematopoietic stem and progenitor cells, leukemic cells, and immune populations

Conduct high-dimensional flow cytometry experiments, including panel design, staining, acquisition, compensation, and basic downstream analysis, with an emphasis on hematopoietic and immune phenotyping

Assist with T cell-based functional assays, CAR-T cell generation, and immune effector testing in hematologic and solid tumor models

Participate in murine models of leukemia and cancer, including injections, monitoring, bone marrow and tissue collection, and downstream analyses

Perform immunohistochemistry, Western blotting, tissue culture, and related assays to support mechanistic studies

Collect, analyze, and interpret experimental data; assist in developing and optimizing new or revised methodologies relevant to hematopoietic and immune research

Perform critical analysis of the scientific literature related to hematology, leukemia, and immuno-oncology projects

Contribute to the preparation of manuscripts, figures, grant applications, and presentations for national meetings and workshops

Maintain accurate records of protocols, results, and inventories; support data organization and presentation

Assist with laboratory operations, including inventory management, procurement of supplies, routine maintenance, and coordination of equipment servicing

Train and support research staff as needed and participate actively in lab meetings, troubleshooting, and protocol optimization

Perform additional duties as assigned

Qualification

Hematopoietic assaysHigh-dimensional flow cytometryMolecular biology techniquesCAR-T cell generationGene editing (CRISPR-Cas9)Murine modelsScientific curiosityWillingness to learnAttention to detailOrganizational skills

Required

Bachelor's degree in Biology, Immunology, Molecular Biology, or a related field

1 year of prior experience in a research laboratory performing hematopoietic, leukemia, or immune-based assays, including molecular biology and/or cellular immunology techniques

Comfort working with human and murine blood and bone marrow samples and biosafety level 2 materials

Successful completion of a background check

Preferred

Experience with bone marrow-derived cells, hematopoietic stem/progenitor cell assays, or leukemia models

Proficiency in high-dimensional flow cytometry (≥20 colors), including panel design, compensation, and gating strategies

Hands-on experience with T cell transduction, CAR constructs, or gene-editing approaches

Prior experience with murine models of leukemia or immune response

Strong organizational skills, attention to detail, and willingness to learn and adapt to evolving experimental needs

Company

The Ohio State University Wexner Medical Center

Glassdoor3.6

The Ohio State University Wexner Medical Center is personalizing health care to meet the needs of each patient. It is a sub-organization of The Ohio State University.

Founded in 1834

Columbus, Ohio, USA

10001+ employees

http://wexnermedical.osu.edu/

H1B Sponsorship

The Ohio State University Wexner Medical Center has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)

Distribution of Different Job Fields Receiving Sponsorship

Represents job field similar to this job

Trends of Total Sponsorships

2024 (3)

2023 (7)