Staff / Principal Data Scientist (Machine Learning and Statistical Modeling) jobs in United States
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Adela, Inc. · 8 hours ago

Staff / Principal Data Scientist (Machine Learning and Statistical Modeling)

Adela, Inc. is dedicated to transforming cancer care through innovative blood tests. They are seeking a highly motivated Staff or Principal Data Scientist to lead the development of novel algorithms that translate raw signal from their whole-methylome platform into actionable insights, collaborating across teams to enhance cancer management solutions.

BiotechnologyHealth CareHealth DiagnosticsMedical
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Responsibilities

Design, implement, and validate machine learning and statistical models supporting Adela’s Cancer Management portfolio (MRD, response monitoring, phenotyping, response prediction)
Analyze sequencing data to quantify signal versus noise, identify assay limitations (batch effects, coverage bias, cross-sample contamination), and define mitigation strategies
Participate and lead cross-functional projects with assay R&D, clinical development, operations, and software engineering to drive product improvements and scale analyses into production
Establish and maintain reproducible workflows (code + data versioning + documentation) and best practices for analysis and model validation
Act as a technical leader who strengthens the team by mentoring peers, sharing knowledge, and introducing new practices that elevate our data science capabilities
Communicate results clearly to scientific and non-scientific stakeholders both internally and externally

Qualification

Statistical modelingMachine learningPythonRHigh-plex omicsNGS dataLiquid biopsy experienceCancer genomicsMolecular diagnosticsLeadership skillsCommunication skillsProblem solvingCross-functional collaboration

Required

PhD in data science, statistics, bioinformatics, computational biology, electrical engineering, computer science, mathematics, or a related quantitative field — or MS with commensurate industry experience and track record
6+ years of relevant experience inclusive of post-graduate training (adjustable by level: Staff = min 6 years, Principal = min 8 years) working with high-plex omics or NGS data
Expertise in statistical modeling, signal processing, and machine learning for biological data
Proficiency in Python and/or R and experience with scientific computing libraries (such as scikit-learn, PyTorch/TF, Stan, NumPy, Bioconductor, etc.)
Strong problem solving, leadership, and communication skills; track record of cross-functional collaboration

Preferred

Prior experience in liquid biopsy / MRD, cancer genomics, or molecular diagnostics

Company

Adela, Inc.

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Adela’s mission is to develop innovative and accessible technologies that harness biology and change the way we diagnose and treat disease.

Funding

Current Stage
Early Stage
Total Funding
$108M
Key Investors
F-Prime
2023-09-25Series A· $48M
2021-06-23Series A· $60M

Leadership Team

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Lisa Alderson
Chief Executive Officer
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Company data provided by crunchbase