Ardelyx, Inc. · 20 hours ago
Manager, Infrastructure Engineering
Waltham, Massachusetts
Full-time
Onsite
Senior Level, Lead/Staff
$162K/yr - $198K/yr
12+ years expArdelyx, Inc. is a biopharmaceutical company focused on developing innovative medicines. The Manager, Infrastructure Engineering will lead a team of engineers, overseeing the design and operations of the company's hybrid cloud and on-prem infrastructure while ensuring high availability and security.
BiotechnologyHealth CareMedical
Responsibilities
Lead, coach, and develop a team of infrastructure engineers, including performance management, career development, and day-to-day guidance
Set priorities, assign work, and manage team capacity to ensure delivery aligned with business goals and timelines
Foster a collaborative, high-performing engineering culture focused on ownership, accountability, documentation, and continuous improvement
Oversee the design, deployment, and ongoing operation of cloud and on-prem infrastructure, including compute, storage, networking, and identity platforms
Develop and execute infrastructure roadmaps that support scalability, reliability, security, and regulatory requirements
Drive modernization initiatives, including automation, cloud adoption, observability improvements, and lifecycle management
Ensure consistent execution of operational best practices, including patching, configuration baselines, and system updates
Own incident management execution, including monitoring, alerting, escalation, and efforts to reduce MTTD/MTTR
Partner with Security, Compliance, Applications, Service Desk, and business stakeholders to deliver integrated, secure solutions
Manage infrastructure vendors and service providers, ensuring SLA adherence, effective escalation, and value delivery
Qualification
Required
Bachelor's degree in Information Technology, Computer Science, Engineering, or related field with 12+ years of hands-on infrastructure engineering or systems engineering experience or equivalent experience
3–5+ years of experience leading, mentoring or managing infrastructure engineering teams and junior staff
Strong operational ownership of on-prem, cloud, and hybrid infrastructure
Proven experience with Windows Server, Active Directory, virtualization, and core networking
Hands-on scripting and automation experience (PowerShell, Python, or Bash)
Experience participating in incident, change, and problem management
Ability to work independently on complex technical issues and mentor junior staff
Strong documentation and cross-team communication skills
Preferred
Relevant certifications preferred (Microsoft, VMware, AWS, Azure, Cisco, FortiNet, PaloAlto, etc.)
Benefits
401(k) plan with generous employer match
12 weeks of paid parental leave
Up to 12 weeks of living organ and bone marrow leave
Equity incentive plans
Health plans (medical, prescription drug, dental, and vision)
Life insurance and disability
Flexible time off
Annual Winter Holiday shut down
At least 11 paid holidays
Company
Ardelyx, Inc.
Ardelyx was founded with a mission to discover, develop and commercialize innovative, first-in-class medicines that meet significant unmet medical needs.
201-500 employees
H1B Sponsorship
Ardelyx, Inc. has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
2024 (1)
2022 (1)
2020 (1)
Funding
Current Stage
Public CompanyTotal Funding
$557.68MKey Investors
HealthCare Royalty PartnersSLR Capital PartnersNew Enterprise Associates
2022-06-30Post Ipo Debt· $20M
2022-02-24Post Ipo Debt· $27.5M
2019-12-12Post Ipo Equity· $125M
Leadership Team
Mike Raab
President & CEO
Elizabeth Grammer
Chief Legal and Administrative Officer
Recent News
2026-01-09
2026-01-09
2026-01-03
Company data provided by crunchbase