Ardelyx, Inc. · 1 day ago
Senior Infrastructure Engineer II
Waltham, Massachusetts
Full-time
Onsite
Senior Level, Lead/Staff
$149K/yr - $182K/yr
10+ years expArdelyx, Inc. is a publicly traded biopharmaceutical company focused on developing innovative medicines for unmet medical needs. The Senior Infrastructure Engineer II serves as the technical authority for the company's infrastructure platforms, leading complex initiatives and mentoring engineers to ensure scalable and resilient systems.
BiotechnologyHealth CareMedical
Responsibilities
Own and lead the full lifecycle of complex, multi-domain infrastructure initiatives from architecture and design through implementation, optimization, and operational readiness
Define, document, and evolve infrastructure architecture standards and reference designs to ensure scalability, resiliency, security, and cost efficiency
Drive long-term infrastructure strategy and modernization initiatives, including automation platforms, cloud-native architectures, and zero-trust-aligned designs
Develop and maintain high-quality architecture artifacts, design documents, and technical roadmaps; clearly articulate tradeoffs and risk to technical and executive audiences
Design and optimize enterprise-scale compute, storage, virtualization, identity, and cloud platforms for performance, reliability, and scalability
Own infrastructure resiliency architecture, including backup, disaster recovery, and business continuity design and testing
Establish and improve observability standards (monitoring, alerting, telemetry) to reduce MTTD and MTTR across platforms
Serve as the highest-level technical escalation point for critical infrastructure, cloud, identity, and network incidents
Mentor and guide Senior Infrastructure Engineer I and other engineers through design reviews, technical coaching, and standards enforcement
Influence capacity planning, automation strategy, and long-term architectural decisions to support sustainable business growth
Qualification
Required
Bachelor's degree in Information Technology, Computer Science, Engineering, or related field with 10+ years of progressive infrastructure engineering experience or equivalent experience
Deep technical expertise across cloud, hybrid, and enterprise infrastructure platforms
Proven experience owning platform architecture and influencing long-term technical strategy
Demonstrated leadership on complex, cross-functional infrastructure modernization initiatives
Strong experience with automation, infrastructure-as-code, and scalable system design patterns
Ability to translate business and risk requirements into durable technical architecture and roadmaps
Recognized as a technical authority and mentor across engineering teams
Proven experience defining and influencing engineering standards, patterns, and best practices across the organization
Preferred
Advanced degree in Information Technology, Computer Science, Engineering, or related field
Advanced or expert-level certifications (Azure Architect, AWS Solutions Architect, VMware, HyperV)
Benefits
401(k) plan with generous employer match
12 weeks of paid parental leave
Up to 12 weeks of living organ and bone marrow leave
Equity incentive plans
Health plans (medical, prescription drug, dental, and vision)
Life insurance and disability
Flexible time off
Annual Winter Holiday shut down
At least 11 paid holidays
Company
Ardelyx, Inc.
Ardelyx was founded with a mission to discover, develop and commercialize innovative, first-in-class medicines that meet significant unmet medical needs.
201-500 employees
H1B Sponsorship
Ardelyx, Inc. has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
2024 (1)
2022 (1)
2020 (1)
Funding
Current Stage
Public CompanyTotal Funding
$557.68MKey Investors
HealthCare Royalty PartnersSLR Capital PartnersNew Enterprise Associates
2022-06-30Post Ipo Debt· $20M
2022-02-24Post Ipo Debt· $27.5M
2019-12-12Post Ipo Equity· $125M
Leadership Team
Mike Raab
President & CEO
Elizabeth Grammer
Chief Legal and Administrative Officer
Recent News
2026-01-09
2026-01-09
2026-01-03
Company data provided by crunchbase