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Flagship Pioneering · 5 hours ago

IT Enterprise Solutions Architect

Cambridge, MA

Full-time

Onsite

Mid, Senior Level

$76K/yr - $104K/yr

Flagship Pioneering is a biotechnology company that invents and builds platform companies that change the world. They are seeking a hands-on, strategically minded Enterprise Architect / Solutions Architect to design and operationalize the Enterprise IT Framework, connecting business processes, systems, data, and governance across the organization.

FinanceFinancial ServicesVenture Capital

H1B Sponsor Likely

Responsibilities

Enterprise IT Framework Leadership

Design, implement, and govern the Enterprise IT Framework—linking business processes, applications, data, and governance mechanisms across the enterprise

Define the Purpose and Objectives of the framework, ensuring all technology investments and operational processes align with Flagship’s strategic outcomes

Establish core architectural layers (Business Process, Application & Systems, Data & MDM) and integrate them into the IT operating model

Lead collaboration across IT, Finance, HR, and Operations to align technology with business capabilities and process maturity

Develop an execution roadmap for continuous improvement and scalability

Business Process & Application Architecture

Map enterprise business capabilities and identify process standardization and integration opportunities

Build and maintain the application architecture blueprint, defining systems of record, systems of engagement, and integration touchpoints

Support application lifecycle management, including rationalization, consolidation, and modernization initiatives

Partner with business process owners to ensure system design aligns with operational needs and strategic priorities

Data & Master Data Governance

Lead the establishment of Master Data Management (MDM) practices and supporting technology

Define data ownership, stewardship, and quality standards across key domains (Employee, Vendor, Customer, Product, etc.)

Partner with business and IT teams to enforce consistent data creation, validation, and integration across systems

Support analytics and reporting functions by ensuring data integrity, compliance, and accessibility

Governance & Policy Framework

Stand up an IT Governance Committee and associated architecture review processes

Develop and maintain enterprise-wide IT policies, standards, and procedures, covering integration development, security, access, data management, and system lifecycle

Define governance cycles (e.g., Architecture Review Board, annual portfolio reviews) and ensure decisions are documented, auditable, and transparent

Collaborate with cybersecurity and compliance teams to align policies with external standards (SOC, ISO, GDPR, SOX, etc.)

Integration & Data Strategy Execution

Design and implement system integrations between enterprise platforms and SaaS tools using platforms such as Workato or Power Platform

Ensure integrations are scalable, secure, and aligned with architectural standards

Document data flow and application interdependencies as part of the enterprise data architecture

Strategic Alignment & Continuous Improvement

Align enterprise architecture initiatives with Flagship’s IT Strategic Goals—operational efficiency, scalability, innovation, and compliance

Define and track metrics and KPIs to measure architectural maturity, integration efficiency, and governance compliance

Continuously assess and optimize architecture components through a structured Assess → Design → Implement → Govern → Optimize cycle

Qualification

Enterprise FrameworksIntegration PlatformsData GovernanceCloud TechnologiesTechnical CertificationsLife Sciences ExposureCommunication SkillsCross-Functional Leadership

Required

Experience architecting and implementing enterprise frameworks that integrate processes, applications, and data

Proven ability to translate business strategy into executable technology roadmaps

Strong working knowledge of enterprise systems (ERP, HCM, MDM) and cloud technologies

Hands-on experience with integration platforms (e.g., Workato)

Familiarity with governance structures and standards development (e.g., ITSM, SOX, ISO, TOGAF)

Excellent communication skills—capable of engaging executives and technical teams alike

Bachelor's or Master's degree in Computer Science, Information Systems, or a related field

Preferred

Experience building enterprise frameworks or MDM programs from the ground up

Exposure to life sciences or innovation-driven organizations

Technical certifications (e.g., TOGAF, AWS/Azure Architect, Workato)

Demonstrated ability to lead cross-functional governance committees

Benefits

Healthcare coverage

Annual incentive program

Retirement benefits

A broad range of other benefits

Company

Flagship Pioneering

Glassdoor3.3

Flagship Pioneering is a venture capital firm that invests in life sciences and healthcare companies.

Founded in 2000

Cambridge, Massachusetts, USA

501-1000 employees

http://flagshippioneering.com

H1B Sponsorship

Flagship Pioneering has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)

Distribution of Different Job Fields Receiving Sponsorship

Represents job field similar to this job

Trends of Total Sponsorships

2025 (8)

2024 (4)

2023 (4)

2022 (4)

2021 (1)