Bayer · 22 hours ago
Computational Biologist, Principal Scientist - CVRI
Cambridge, MA
Full-time
Onsite
Senior Level, Lead/Staff
$125K/yr - $187K/yr
5+ years expBayer is a visionary company dedicated to solving the world’s toughest challenges in health and agriculture. They are seeking a Principal Scientist - Computational Biologist to evaluate therapeutic hypotheses and conduct quantitative analyses of multi-omics data for cardiovascular, renal, and immunology therapeutic areas.
BiotechnologyChemicalHealth CareLife SciencePharmaceutical
Responsibilities
Evaluate and contextualize the molecular evidence supporting a therapeutic hypothesis with relevant internal and external multi-omics data (DNA, RNA, proteomics, metabolomics, imaging, etc)
Contribute to Project Team scientific strategy and prosecution of critical path objectives, such as the identification of novel targets, biomarkers, or patient selection hypotheses. These contributions use state-of-the art computational biology methods to analyze large and complex human data sets
Deliver biological insights on therapeutic assets and disease biology understanding to Project Teams, who apply these insights towards stage-gate decisions, portfolio prioritization, and/or submissions to Health Authorities
Educate Project Teams on innovations in disease understanding in the CardioVascular, renal and immunology Therapeutic Areas
Develop, evaluate, implement, and apply Best Practices for the execution and validity of quantitative analyses, integration, visualizations, and interpretation of multi-omics data. Demonstrate a growth mindset towards updating Best Practices with the emergence of new experimental or computational technologies
Build cross-functional relationships to collaboratively partner across Pharma R&D and effectively network within disease understanding and data science communities of experts
Qualification
Required
PhD degree with post-graduation experience in Sciences (Bioinformatics, Computational Biology, Biology, Chemistry, Genetics, Computer Science, Informatics, or other related quantitative discipline) with very strong computational focus
Demonstrated experience in statistical analysis of DNA-seq, RNA-seq, proteomics, single-cell, or imaging datasets with proficiency in a programming environment (such as R or Python)
Demonstrated hands-on experience in analysis of large scale proteomics, metabolomics datasets
Demonstrated peer-reviewed publications in computational biology
Expert level of proficiency to choose fit-for-purpose quantitative analyses
Strong analytical thinking and scientific rigor
Strong communication competencies to include presentations and delivery of complex quantitative analyses in a clear, concise, and actionable manner to broad audiences and key stakeholders across multiple functions or to external partners
Learning agility, highly self-motivated, with an aspiration of continuous improvement of oneself and others
Evidence of providing tactical and strategic guidance to the pharma portfolio or data science ecosystem
Demonstrated ability to propose, catalyze, and implement the development of interdisciplinary, systematic solutions that create business value
Capability to present even very complex issues clearly and convincingly to project teams or decision bodies. Good communication skills. Can manage a high degree of complexity
Demonstrates advanced business acumen, people and project leadership competencies, and technical expertise
Preferred
5+ years of post-graduation experience in Sciences (Bioinformatics, Computational Biology, Biology, Chemistry, Genetics, Computer Science, Informatics, or other related quantitative discipline) with very strong computational focus
3+ years industry experience in drug development or biotech role with clear understanding of applying multi-omics data analyses to advance a portfolio of drug discovery or clinical development projects
Benefits
Healthcare
Vision
Dental
Retirement
PTO
Sick leave
Company
Bayer
Bayer is a life science company that specializes in the areas of health care and agriculture.
10001+ employees
H1B Sponsorship
Bayer has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (62)
2024 (71)
2023 (76)
2022 (141)
2021 (138)
2020 (117)
Funding
Current Stage
Public CompanyTotal Funding
$9.34BKey Investors
Bank of AmericaBill & Melinda Gates FoundationTemasek Holdings
2025-09-26Post Ipo Debt· $331.5M
2024-12-06Post Ipo Debt· $5.29B
2022-11-08Grant· $12M
Leadership Team
Wolfgang Nickl
Member of the Board of Management of Bayer AG and CFO
Abi Abitorabi
VP, CGT Platform Implementation Lead
Recent News
2026-01-16
Pharmaceutical Technology
2026-01-16
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