Quantum-Si · 14 hours ago
Staff Engineer, System Integration
San Diego, CA
Full-time
Onsite
Lead/Staff
$175K/yr - $190K/yr
8+ years expQuantum-Si is looking for a highly motivated and experienced Staff Engineer, System Integration to make an impact on the development of their next generation protein sequencer. The role involves ensuring continuous operation of test stands, designing Python scripts for diagnostics, collaborating with teams, and integrating hardware and software components.
BiotechnologyHealth DiagnosticsLife ScienceSemiconductor
Responsibilities
Ensure continuous operation and minimal downtime of test stands and alpha-stage instruments by performing rapid troubleshooting and system-level diagnostics
Design and implement Python scripts and utilities to support system-level diagnostics and troubleshooting of next generation protein sequencing instruments
Collaborating with design and development teams to implement fixes and upgrades
Integrate hardware and control software. Develop and execute integration test plans to verify system functionality and performance
Act as a bridge between hardware, software, and scientific teams. Communicate integration challenges and solutions clearly across disciplines
Grasp how subsystems (optics, electronics, software, biology) interact. Predict how changes in one domain affect others
Use structured methods to isolate issues. Comfortable with iterative debugging and hypothesis testing. This includes the ability to perform complex data analysis
Understand the scientific principles behind the instrument’s function. Interpret experimental data to validate or refute system behavior
Develop novel workarounds or design tweaks when standard solutions fail. Think outside the box while staying grounded in engineering principles
Qualification
Required
B.S. in Biomedical Engineering, Biological Engineering, Electrical Engineering, or related field
8+ years experience
Programming experience, such as Python, C or C++
Strong attention to detail, ability to follow complex protocols accurately and reproducibly
Ability to analyze complex, ambiguous problems. Evaluate multiple hypotheses and test systematically
Excellent communication skills are required, and the ability to interact well in group meetings/working environments
Self-starter with a relentless work ethic who can work independently, but who also functions well in a collaborative team environment
Demonstrated team skills: ability to maintain excellent rapport with colleagues in the face of tight development schedules
Travel: Up to 10%
Preferred
PhD Preferred
Experience with next generation sequencing workflows
Opto-mechanical systems, including precision alignment of optics
Experience working in start-up environments
Benefits
Discretionary bonus program
Equity as part of the compensation package
Visa assistance for qualified candidates
Company
Quantum-Si
Quantum-Si is transforming proteomics with a benchtop platform that brings single-molecule protein analysis to every lab, everywhere.
51-200 employees
H1B Sponsorship
Quantum-Si has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (3)
2024 (3)
2023 (5)
2022 (8)
2021 (3)
2020 (2)
Funding
Current Stage
Public CompanyTotal Funding
$525M2025-07-03Post Ipo Equity· $50M
2025-01-03Post Ipo Equity· $50M
2021-06-11Post Ipo Equity· $425M
Leadership Team
Todd Rearick
Chief Technology Officer
Jeff Keyes
Chief Financial Officer
Recent News
2025-12-02
Company data provided by crunchbase