Senior/Principal Scientist, Medicinal Chemistry jobs in United States
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Flagship Pioneering · 23 hours ago

Senior/Principal Scientist, Medicinal Chemistry

Expedition Medicines is a biotechnology company pioneering Protein Editing to transform health care and sustainability. The role involves leading medicinal chemistry strategy and collaborating with cross-functional teams, including machine learning, to deliver on project goals.

FinanceFinancial ServicesVenture Capital
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H1B Sponsor Likelynote

Responsibilities

Design and deliver medicinal chemistry strategy on project(s)
Optimize small molecules through analysis of biochemical, biological, and ADME assay data
Manage chemistry CROs for timely delivery of synthetic efforts
Collaborate with cross-functional teams for project needs in high-paced data-driven environment
Collaborate with machine learning team for delivery against medicinal chemistry strategy
Contribute to patent applications and scientific publications

Qualification

Medicinal ChemistrySynthetic Organic ChemistryDrug Discovery ExperienceManaging Chemistry CROsCollaboration with Machine LearningCommunication SkillsInterpersonal Skills

Required

PhD in synthetic organic or medicinal chemistry with at least 5 years' drug discovery experience in pharmaceutical industry or BS/BA in chemistry with at least 10 years' experience in pharmaceutical industry
Strong communication and interpersonal skills

Preferred

Strong modern synthetic background preferred with knowledge of state-of-the-art organic chemistry methodologies
Experience managing external chemistry CROs
Experience collaborating with machine learning teams preferred
Experience with both traditional small molecules and beyond-rule-of-5 therapeutic modalities is a plus

Benefits

Healthcare coverage
Annual incentive program
Retirement benefits
Broad range of other benefits

Company

Flagship Pioneering

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Flagship Pioneering is a venture capital firm that invests in life sciences and healthcare companies.

H1B Sponsorship

Flagship Pioneering has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (8)
2024 (4)
2023 (4)
2022 (4)
2021 (1)

Funding

Current Stage
Late Stage

Leadership Team

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Noubar Afeyan
Founder and CEO
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Chuck Carelli
Chief Financial Officer
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Company data provided by crunchbase