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AstraZeneca · 19 hours ago

Scientist, High Throughput Antibody Production

US - Waltham - MA

Full-time

Onsite

Entry, Mid Level

$87K/yr - $131K/yr

1+ years exp

AstraZeneca is a global organization committed to discovering and optimizing next-generation biologics. As a Scientist in the Waltham team, you will execute high-throughput antibody production and purification, ensuring efficient delivery of antibody therapeutics.

BiopharmaBiotechnologyHealth CareMedicalPharmaceuticalPrecision Medicine

Comp. & Benefits

H1B Sponsor Likely

Responsibilities

Executing well-validated SOPs for high-throughput antibody production and purification

Delivering microgram-to-milligram quantities of antibody therapeutics efficiently and reliably

Managing scheduled production campaigns

Ensuring instrumentation readiness

Performing routine QC

Compiling comprehensive data packages for project teams

Qualification

Antibody expressionUPLCMolecular biologyMammalian cell cultureLiquid handlers operationLaboratory logisticsProtein purification technologiesData handling scriptingEffective communicationAttention to detail

Required

Master's degree with 1+ years of experience in antibody expression/purification, UPLC, or molecular biology

Bachelor's degree with 3+ years of experience in antibody expression/purification, UPLC, or molecular biology

Demonstrated experience executing standardized high-throughput expression and purification workflows for antibodies or antibody-like proteins at microgram-to-milligram scale

Hands-on operation of liquid handlers (Hamilton or Lynx preferred) using validated methods with integrated automation platforms (Biosero/Green Button Go) a plus

Proficiency in mammalian cell culture (CHO and HEK293), aseptic technique, and transient expression

Experience with sample tracking and laboratory logistics/LIMS software; comfort with barcode-driven workflows

Ability to plan production runs, manage consumables, and meet deadlines in a fast-paced environment

Strong attention to detail, documentation rigor, and adherence to SOPs and QC acceptance criteria

Effective communication and collaboration across cross-functional teams

Preferred

Working knowledge of protein purification technologies and common analytical methods (e.g., SEC-UPLC, LC-MS, SDS-PAGE, CE)

Familiarity with lab automation scheduling software; Green Button Go preferred

Basic scripting for data handling (e.g., Python, Jupyter) is a plus, not required

Exposure to imaging or flow cytometry platforms and analysis tools (iQue, Attune, FlowJo) is beneficial for specific assays but not central to the role

Benefits

Eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles

Qualified retirement programs

Paid time off (i.e., vacation, holiday, and leaves)

Health, dental, and vision coverage in accordance with the terms of the applicable plans

Company

AstraZeneca

Glassdoor4.1

AstraZeneca is a pharmaceutical company that discovers, develops, manufactures, and markets prescription medicines. It is a sub-organization of Investor.

Founded in 1999

Cambridge, Cambridgeshire, GBR

10001+ employees

https://www.astrazeneca.com

H1B Sponsorship

AstraZeneca has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)

Distribution of Different Job Fields Receiving Sponsorship

Represents job field similar to this job

Trends of Total Sponsorships

2021 (2)

2020 (11)