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AstraZeneca · 17 hours ago

Senior Scientist

Durham, NC

Full-time

Hybrid

Mid, Senior Level

3+ years exp

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialization of prescription medicines for some of the world’s most serious diseases. The Senior Scientist role is responsible for supporting the development of pressurized metered dose inhalers and oral solid dosage forms, requiring expertise in drug development and strong collaboration skills.

BiopharmaBiotechnologyHealth CareMedicalPharmaceuticalPrecision Medicine

Comp. & Benefits

H1B Sponsor Likely

Responsibilities

Collaborate with both internal and external partners (e.g. analytical, cRO/cMOs, academic institutions, manufacturing, formulation, device, quality assurance, statistics, and regulatory affairs) to effectively deliver on project and team objectives

Effectively plan, complete and communicate technical development activities within AZ project teams

Lead/Author complex technical protocols for the development of drug products using both internal and external resources

Lead/participate in technical development teams with focus on product development, characterization, root cause analysis and risk mitigation

Lead/participate in drug product project technical investigations and provide analysis/recommendations to team

Prioritize and interpret large data sets and communicate data impact or value to senior R&D leadership

Contribute to/and or lead continuous improvement projects and other GPD initiatives

Maintain lab notebooks following SOP requirements and keep clear and complete records. Ensure GMP/GLS compliance

Maintain lab equipment and lab environments following SOP requirements and keep clear and complete records. Ensure GMP/GLS compliance

Complete procurement activities for lab/project (Requestioning, PO generation, invoicing)

Ability to work in a laboratory environment for up to 50% of time, conducting characterization testing, formulation development, spray drying development activities

Ability to work in office environment and familiarity with PCs (MS office proficiency required)

Qualification

Drug development experienceAnalytical characterization techniquesTechnical protocol authoringRegulatory document authoringLean/Six Sigma familiarityJMP statistical softwareCommunication skillsCollaboration skillsProblem-solving skills

Required

Bachelor's Degree

Minimum 3+ years of experience

Excellent written and verbal communication skills

Effectively plan, complete and communicate technical development activities within AZ project teams

Working knowledge of key analytical characterization techniques (e.g. Karl Fischer moisture analysis, HPLC, pH, solid state particle analysis)