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University of Pennsylvania · 4 hours ago

Senior, Research Investigator

Smilow Center for Translational

Full-time

Onsite

Senior Level

$80K/yr - $95K/yr

5+ years exp

The University of Pennsylvania is a world-renowned leader in education, research, and innovation. They are seeking a Senior Research Investigator to design, manufacture, and test new constructs for in vivo T cell and hematopoietic stem cell transduction, while also overseeing and teaching experimental skills to junior lab members.

Continuing EducationEdTechEducationSTEM EducationUniversities

Growth Opportunities

Responsibilities

Molecular biology: cloning

Viral (e.g. lentiviral) production, titration, characterization and validation

In vitro T cell and HSC transduction: optimization of conditions, demonstration of on-target specificity

In vivo experiments: injection of mice, in vivo imaging, bleeding/organ extraction and analysis using flow, microscopy and transcriptomic techniques (assisted by other lab members as needed)

On-boarding, teaching, mentoring and supervision of junior lab members e.g. graduate students

Perform data analysis and other aspects of quantitative and qualitative research as well as theoretical research

Review, edit, format, and write manuscripts for publication and of grant proposals

Assist with and often direct the design and implementation of original surveys

Perform data collection and management

Administer literature reviews

Other research and administrative duties

Oversee laboratory operations

Assist PI, graduate students, and postdoctoral fellows with experimental procedures and analysis

Grant development

Data analysis

Conduct biochemical and molecular biology assays, including chemical extractions, PCR, RT-PCR, sub-cloning, and Western blotting, animal ,Protocol Development

Other duties and responsibilities as assigned