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AstraZeneca · 4 hours ago

Executive Director, Clinical Operations Program Management (CVRM)

US - Gaithersburg - MD

Full-time

Hybrid

Director/Executive

$284K/yr - $427K/yr

AstraZeneca is a leading pharmaceutical company seeking a motivated Executive Director for Clinical Operations Program Management in the Cardiovascular, Renal & Metabolic (CVRM) domain. The role involves leading global program directors, translating CVRM strategy into operational objectives, and ensuring the delivery of clinical trials on time and within budget.

BiopharmaBiotechnologyHealth CareMedicalPharmaceuticalPrecision Medicine

Comp. & Benefits

Responsibilities

Functional leadership: line‑manage and develop Program Management Senior Directors; recruit, resource plan, and build capabilities

Coaching and culture: mentor teams, champion new ways of working, foster collaboration, accountability, and continuous improvement

Strategy translation: convert CVRM strategy into forward‑looking clinical operations objectives across early and late programs

Operational excellence: ensure robust strategic and operational planning; lead operational planning reviews; secure successful asset transitions from CDID to Phase III

Performance: deliver portfolio to time, quality, and cost; proactively identify trends, risks, and opportunities using internal and external data

Enterprise impact: represent Clinical Operations at governance and decision bodies (e.g., DRC, PRC); serve on Steering Committees and cross‑functional initiatives

Best practices: drive clarity and consistency across strategic processes; establish standards for trial delivery; share lessons learned across TAs

Insight‑driven recommendations: conduct rigorous analyses to inform resourcing and delivery optimization; provide clear, actionable guidance to leadership

AI enablement: leverage AI and advanced analytics to enhance efficiency of clinical operations resources and decision quality

Partnerships: engage AROs, CROs, labs, KEEs, and development partners; represent Clinical Operations at congresses, investigator meetings, and with health authorities

Qualification

Global drug development leadershipProgram managementComplex study designAIAdvanced analyticsFinancial evaluationBusiness planningHigh-impact communicationStrategic influencingClearOrganized thinkingMentoring teamsChange leadershipCollaboration

Required

Bachelor's/Master's in a related discipline; advanced degree preferred

Extensive global drug development leadership across early and late phase; significant program management with complex projects (resourcing, financials, business cases)

Strong understanding of complex study design, TPPs, CDPs, competitive dynamics, pricing, market access, and global regulatory environments

Strategic influencing, clear and organized thinking, financial evaluation of assets/brands, business planning, high-impact communication and presentation

Proven ability to lead, mentor, and develop diverse high-performing teams; collaborate across disciplines; plan, prioritize, and deliver

Comfortable utilizing AI for ethical, accurate data analyses

Willingness for domestic and international travel

Preferred

Driving efficiency and implementing new ways of working

Submission experience; insights from Japan and China delivery

Leading teams through change; clinical environment insight

Benefits

Short-term incentive bonus opportunity

Equity-based long-term incentive program (salaried roles)

Retirement contribution (hourly roles)

Commission payment eligibility (sales roles)

Qualified retirement program [401(k) plan]

Paid vacation and holidays

Paid leaves

Health benefits including medical, prescription drug, dental, and vision coverage

Company

AstraZeneca

Glassdoor4.1

AstraZeneca is a pharmaceutical company that discovers, develops, manufactures, and markets prescription medicines. It is a sub-organization of Investor.

Founded in 1999