Executive Director, Clinical Operations Program Management (CVRM) jobs in United States
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Alexion Pharmaceuticals, Inc. · 7 hours ago

Executive Director, Clinical Operations Program Management (CVRM)

positionWaltham, Massachusetts, United States of America
timeFull-time
remoteHybrid
seniorityDirector/Executive
money$284K/yr - $427K/yr

Alexion Pharmaceuticals, Inc. is seeking a motivated, collaborative, data‑driven enterprise leader to shape and deliver the Cardiovascular, Renal & Metabolic (CVRM) clinical operations portfolio. As Executive Director, Clinical Operations Program Management, you will lead Senior/Global Program Directors across early and late development, translating CVRM strategy into clear operational objectives and driving disciplined decision-making to deliver trials to time, quality, and cost.

BiotechnologyHealth CareMedicalTherapeutics
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Comp. & Benefits
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H1B Sponsor Likelynote

Responsibilities

Functional leadership: line‑manage and develop Program Management Senior Directors; recruit, resource plan, and build capabilities
Coaching and culture: mentor teams, champion new ways of working, foster collaboration, accountability, and continuous improvement
Strategy translation: convert CVRM strategy into forward‑looking clinical operations objectives across early and late programs
Operational excellence: ensure robust strategic and operational planning; lead operational planning reviews; secure successful asset transitions from CDID to Phase III
Performance: deliver portfolio to time, quality, and cost; proactively identify trends, risks, and opportunities using internal and external data
Enterprise impact: represent Clinical Operations at governance and decision bodies (e.g., DRC, PRC); serve on Steering Committees and cross‑functional initiatives
Best practices: drive clarity and consistency across strategic processes; establish standards for trial delivery; share lessons learned across TAs
Insight‑driven recommendations: conduct rigorous analyses to inform resourcing and delivery optimization; provide clear, actionable guidance to leadership
AI enablement: leverage AI and advanced analytics to enhance efficiency of clinical operations resources and decision quality
Partnerships: engage AROs, CROs, labs, KEEs, and development partners; represent Clinical Operations at congresses, investigator meetings, and with health authorities

Qualification

Global drug development leadershipProgram managementComplex study designAIAdvanced analyticsFinancial evaluationBusiness planningStrategic influencingHigh-impact communicationChange leadershipMentoring teams

Required

Bachelor's/Master's in a related discipline; advanced degree preferred
Extensive global drug development leadership across early and late phase; significant program management with complex projects (resourcing, financials, business cases)
Strong understanding of complex study design, TPPs, CDPs, competitive dynamics, pricing, market access, and global regulatory environments
Strategic influencing, clear and organized thinking, financial evaluation of assets/brands, business planning, high-impact communication and presentation
Proven ability to lead, mentor, and develop diverse high-performing teams; collaborate across disciplines; plan, prioritize, and deliver
Comfortable utilizing AI for ethical, accurate data analyses
Willingness for domestic and international travel

Preferred

Driving efficiency and implementing new ways of working
Submission experience; insights from Japan and China delivery
Leading teams through change; clinical environment insight

Benefits

Short-term incentive bonus opportunity
Equity-based long-term incentive program (salaried roles)
Retirement contribution (hourly roles)
Commission payment eligibility (sales roles)
Qualified retirement program [401(k) plan]
Paid vacation and holidays
Paid leaves
Health benefits including medical, prescription drug, dental, and vision coverage

Company

Alexion Pharmaceuticals, Inc.

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Alexion, AstraZeneca Rare Disease is focused on pioneering new possibilities for the rare disease community.
dateFounded in 1992
location
Boston, Massachusetts, USA
people-size1001-5000 employees
web-link
https://alexion.com

H1B Sponsorship

Alexion Pharmaceuticals, Inc. has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (49)
2024 (57)
2023 (51)
2022 (29)
2021 (27)
2020 (17)

Funding

Current Stage
Public Company
Total Funding
$5.8M
2020-12-12Acquired
1999-02-12Post Ipo Equity· $5.8M
1996-02-29IPO

Leadership Team

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Frederic Chereau
SVP, Strategy and Business Development
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Imran Shakur
Director, IRT and Technology Lead
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