Senior Scientist, Translational Science & Biomarkers jobs in United States
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ImmunEdge · 1 day ago

Senior Scientist, Translational Science & Biomarkers

ImmunEdge is a biopharmaceutical company committed to developing novel therapeutics for patients with serious or life-threatening diseases. The Senior Scientist, Translational Science & Biomarkers will contribute to preclinical and clinical programs by developing and validating tissue-based biomarker assays, collaborating with cross-functional teams, and driving scientific strategy in drug discovery and precision medicine.

Biotechnology
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H1B Sponsor Likelynote

Responsibilities

Build our understanding of gene and protein expression profiles for novel oncology biomarkers (ImmunEdge targets and relevant cell types) across different body tissues and tumor types, to help guide future clinical development
Design, validate, and implement single and multiplex immunohistochemistry and ISH assays, including co-proximity assays (e.g. DuoLink PEA)
Manage histopathology lab operations, including organization of reagents and specimens, equipment maintenance, coordinating with vendors, etc
Identify and assess emerging pathology techniques, including spatial transcriptomics and novel multiplex technologies, and either build these capabilities in-house or oversee work performed at CROs
Develop and run digital image analysis workflows for whole slide scans, using software such as HALO or Visiopharm
Contribute to scientific strategy by proposing new hypotheses and supporting the advancement of ImmunEdge’s research and development pipeline
Analyze, interpret, and communicate complex research findings to cross-functional stakeholders with varied scientific backgrounds
Maintain accurate, well-organized records while supporting a safe and compliant lab environment

Qualification

Histopathology expertiseOncology drug developmentImmunologySpatial transcriptomicsDigital pathology image analysisMultiplex technologiesTissue cultureELISAQPCRWestern blotFlow cytometryRecord-keepingTechnical writingOrganizational skills

Required

Ph.D. in Immunology, Pathology, Molecular and Cellular Biology, or a related field, or M.S. with additional years of experience
4+ years of industry experience in oncology drug development, with at least 5 years of total experience working in histology and IHC labs with FFPE samples
Strong technical expertise in histopathology, including multiplex technologies, spatial transcriptomics, and digital pathology image analysis
Proficiency with other standard lab techniques including tissue culture, ELISA, qPCR, western blot, and flow cytometry
Ability to independently oversee scientific activities, solve complex problems, and rigorously analyze and interpret scientific data
Ability to work effectively and collaboratively in a supportive, but dynamic, start-up environment
Excellent communication, technical writing, record-keeping, and organizational skills

Preferred

Experience with bioanalytical (PK) assay development
Primary immune cell culture
Experience with the Leica Bond Rx platform

Benefits

Annual bonus plan
Equity
Comprehensive health (medical, dental, and vision) insurance for our employees and their families
401k plan
FSA plans (medical, dependent)
Employee Assistance Plan
Holiday and paid time off plan

Company

ImmunEdge

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ImmunEdge is a biopharmaceutical company committed to developing novel therapeutics for patients with serious or life-threatening diseases.

H1B Sponsorship

ImmunEdge has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2023 (1)

Funding

Current Stage
Early Stage
Company data provided by crunchbase