Roche · 5 hours ago
Technical Development Scientist II - Analytical Development
San Diego
Full-time
Onsite
Mid, Senior Level
$80K/yr - $150K/yr
5+ years expGenentech, a member of the Roche Group, is seeking an experienced and motivated Technical Development Scientist to join their Analytical Development team in San Diego. The role involves developing and improving cell-based assays for CAR-T cell products and supporting laboratory activities related to process development and product characterization.
BiotechnologyHealth CareHealth DiagnosticsOncologyPharmaceuticalPrecision Medicine
Responsibilities
Develops analytical test method procedures in accordance with relevant guidelines from ICH, USP, EP for cell therapy product GMP release testing and characterization
Supports analytical routine testing, qualification, and validation
Evaluates reagents and supplies to meet QC standards
Co-authors test methods (SOPs), technical reports, and analytical sampling plans
Documents laboratory procedures and experiments with great attention to detail in laboratory notebooks
Performs assays for process assessment and product characterization
Participates in assay transfers to QC and provides lifecycle support
Summarize and present scientific data to project teams
Evaluates alternative technologies to create robust and reproducible analytical methods
Sets up, monitors, samples, and analyzes cell culture processes
Works with R&D teams to gain deeper understanding of the analytical methods for characterization of product critical quality attributes
Qualification
Required
BS or MS degree in a relevant scientific discipline with five plus years of relevant experience in a biotech environment (an equivalent combination of education and experience may be considered)
Experience in human T cell biology with demonstrated proficiency in a broad range of cellular immunology techniques, including cell-based assays, immunoassays, and flow cytometry
Experiences with aseptic cell culture (human primary cells and cell lines) and bio-assay development and/or testing
Ability to follow laboratory procedures with attention to detail, and successfully execute experiments at the bench
Demonstrated ability to maintain detailed lab execution records and perform data analysis
Excellent communication skills, data presentation and interpersonal skills
Basic computer skills in Excel, PowerPoint, and word processing
Attention to detail, initiative, and strong organizational skills
Comfortable in a fast-paced small company environment with reasonable direction and able to adjust workload based upon changing priorities
Preferred
Two plus years of relevant cell therapy industry experience
Foundation in experimental documentation, basic statistical analysis, and data presentation
Exposure in vitro T cell functional assays (potency, cytotoxicity, ELISA, proliferation, Luminex)
Basic skills in molecular techniques including qPCR or ddPCR and electrophoresis
Experience with drafting SOP and forms
Develops assays for cell product release and characterization by designing and executing studies via design of experiment (DoE)
Benefits
A discretionary annual bonus may be available based on individual and Company performance.
This position also qualifies for the benefits detailed at the link provided below.
Company
Roche
Roche is a pharmaceutical and diagnostics company that offers medicines and diagnostic tests for various medical conditions and diseases.
10001+ employees
H1B Sponsorship
Roche has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (12)
2024 (9)
2023 (6)
2022 (2)
2021 (2)
Funding
Current Stage
Public CompanyTotal Funding
$7.79BKey Investors
SoftBankSCALE AINovartis
2021-08-04Post Ipo Equity· $5B
2020-12-07IPO
2020-05-06Post Ipo Equity· $0.5M
Leadership Team
Alan Hippe
Member of the Executive Board - Group CFO
Christine Bakan
Global Head and VP of Software and Bioinformatics, Next Generation Sequencing
Recent News
Pharmaceutical Technology
2026-01-13
2026-01-12
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