Medical College of Wisconsin · 4 hours ago
Research Scientist I - Biophysics Department
Milwaukee, WI
Full-time
Onsite
Mid, Senior Level
5+ years expThe Medical College of Wisconsin is seeking a highly motivated Research Scientist to join their Biophysics Department, focusing on the structural and functional analysis of oncogenic noncoding RNAs. The role involves designing experiments, conducting biochemical assays, and mentoring graduate students in a collaborative research environment.
EducationHigher EducationMedical
Responsibilities
Design and execute experiments to investigate the structure and dynamics of noncoding RNAs using biophysical and structural techniques (e.g., NMR, X-ray crystallography, cryo-EM)
Conduct biochemical assays to study RNA-protein and RNA-small molecule interactions
Perform in vitro transcription, RNA purification, labeling, and structural probing
Analyze experimental data, interpret results, and contribute to manuscript preparation
Present research findings at lab meetings, institutional seminars, and scientific conferences
Mentor graduate students and contribute to training and scientific development within the lab
Assist with the development of grant proposals and collaborative research initiatives
Coordinate research study activities; lead and manage projects
May oversee the work of laboratory personnel, including training and development as well as daily work direction/delegation/prioritizing
Other duties as assigned
Qualification
Required
PhD in a scientific field - in Biochemistry, Biophysics, Structural Biology, Chemistry, Molecular
Knowledge of structural biology, protein expression and purification, and molecular biology
Structural biology software: Phenix, Coot, Chimera, CryoSPARC, Relion
Data utilization, complex problem solving, critical thinking, resource management, and writing skills
Hands-on experience in X-ray crystallography or cryo-EM
Experience in small molecule drug discovery and structure-based drug design
Proven ability to work independently, manage time effectively, and troubleshoot experiments
Excellent written and verbal communication skills
Preferred
5 years of research experience
Experience in protein expression, purification, and RNA–protein complex reconstitution
Exposure to small-molecule screening and medicinal chemistry
Strong publication record in peer-reviewed journals
Benefits
Outstanding Healthcare Coverage, including but not limited to Health, Vision, and Dental. Along with Flexible Spending options
403B Retirement Package
Competitive Vacation and Paid Holidays offered
Tuition Reimbursement
Paid Parental Leave
Employee & Family Assistance Program (EFAP)
Pet Insurance
On campus Fitness Facility, offering onsite classes
Additional discounted rates on items such as: Select cell phone plans, local fitness facilities, Milwaukee recreation and entertainment etc.
Company
Medical College of Wisconsin
Medical College of Wisconsin is a school in Milwaukee.
5001-10000 employees
H1B Sponsorship
Medical College of Wisconsin has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (139)
2024 (70)
2023 (70)
2022 (81)
2021 (67)
2020 (65)
Funding
Current Stage
Late StageTotal Funding
$22.7MKey Investors
US Department of Commerce, Economic Development AdministationNational Institutes of HealthPaula and Rodger Riney Foundation
2024-07-03Grant
2023-08-17Grant
2022-08-25Grant· $5.9M
Leadership Team
John R. Raymond
President and CEO
Recent News
Business Wire
2025-11-05
2025-11-03
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