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Merck · 6 hours ago

Senior Scientist, Molecular Discovery

USA - California - San Diego (Science Park Road)

Full-time

Hybrid

Mid, Senior Level

$106K/yr - $167K/yr

4+ years exp

Merck is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. The Discovery Biologics Department is seeking a Senior Scientist with expertise in measuring macromolecular interactions to support the advancement of therapeutic protein candidates and collaborate within cross-functional teams.

BiotechnologyHealth CareMedicalPharmaceutical

Comp. & Benefits

H1B Sponsored

Responsibilities

Support the advancement of therapeutic protein candidates by applying advanced biophysical and biochemical methods

Characterize macromolecular interactions using biophysical assays including SPR, BLI, and KinExA

Characterize novel therapeutic protein designs with biophysical and in vitro assays, including TR-FRET, DSF, ELISA, and cell-based assays

Explore and apply new protein biophysical assay technologies and strategies as needed

Document experiments in a thorough and timely manner

Collaborate within cross-functional teams and communicate findings to stakeholders

Drive innovation through platform technology development

Collaborate with other teams to integrate new developments into future projects

Qualification

Protein BiochemistryBiophysical TechniquesBiochemical AssaysProtein-Protein InteractionsBiosensor TechnologiesCommunicationAttention to DetailCollaboration Skills

Required

Bachelor's (with 7+ years), Master's (with 4+ years) or Ph.D. in molecule biology, biochemistry, structural biology or related discipline with relevant laboratory experience described below

Strong understanding of protein biochemistry and biophysics

Experience with techniques to measure protein-protein interactions

Experience with developing, executing, and interpreting biophysical and biochemical assays

Demonstrated strong communication skills as well as the ability to multi-task and work collaboratively in a cross-functional team environment

Excellent organizational skills and high attention to detail