Johnson & Johnson Innovative Medicine · 6 hours ago
Principal Scientist, Omics - R&D Data Science & Digital Health – Neuroscience
Spring House, PA
Full-time
Hybrid
Senior Level, Lead/Staff
$117K/yr - $201K/yr
3+ years expJohnson & Johnson Innovative Medicine is dedicated to healthcare innovation and is seeking a Principal Scientist, Omics to focus on Neurodegeneration and Neuropsychiatry. This role involves driving the precision neuroscience strategy by leading projects that utilize bioinformatics, artificial intelligence, and machine learning to link molecular signatures to disease stages and mechanisms.
Pharmaceuticals
Responsibilities
Shape the strategy and implement projects for data-driven identification and evaluation of novel therapeutic targets, patient stratification approaches and precision biomarkers from the perspective of omics data, brain biology, and mechanism of action, drawing upon a combination of internal and external resources
Work in multi-disciplinary teams, composed of discovery scientists, clinicians, computational biologists and biomarker experts to develop precision neuroscience plans across the Neurodegeneration and Neuropsychiatry portfolio, being forward looking and foreseeing a path to launch
Remain current on the constantly evolving landscape of neuroscience, neuropsychiatry, and neurodegeneration, omics, bioinformatics and AI/ML research in search of better strategies for accelerating and prioritizing our portfolio based on biological insights
Build strong relationships with internal partners and key academic collaborators, technology providers, and consortia to position the company at the forefront of data-driven neuroscience
Qualification
Required
PhD in neuroscience, computational biology, bioengineering, biostatistics, or a related field is required
3+ years of progressive industry or academic experience in applying data-driven methods in the context of target discovery and validation, translational science and patient stratification is required
Extensive background working hands-on deriving insights from high-dimensional molecular data – particularly genetic, RNAseq, proteomics and/or single-cell data is required
Proficiency in R, Python, or similar programming languages is required
Proven track record of scientific contributions in this field with first author publications in high-impact journals is required
Experience translating data into strategies and executable action plans is required
Ability to clearly communicate technical work to a diverse audience is required
Up to approximately 10% yearly travel is required (International, Domestic)
Preferred
Background and experience working in Neurodegeneration and/or Neuropsychiatry is strongly preferred
Experience working with and leading interdisciplinary teams through either people or project leadership is preferred
Familiarity with machine learning and innovative AI methodologies is preferred
Strong reputation for driving novel solutions to problems and providing strategic advice is preferred
Familiarity with clinical development processes is preferred
Benefits
Medical
Dental
Vision
Life insurance
Short- and long-term disability
Business accident insurance
Group legal insurance
Consolidated retirement plan (pension)
Savings plan (401(k))
Vacation – up to 120 hours per calendar year
Sick time - up to 40 hours per calendar year
Holiday pay, including Floating Holidays – up to 13 days per calendar year of Work
Personal and Family Time - up to 40 hours per calendar year
Company
Johnson & Johnson Innovative Medicine
Johnson and Johnson Innovative Medicine focuses on developing medical solutions for some of the challenging diseases and medical conditions.
10001+ employees
Funding
Current Stage
Late StageLeadership Team
Molly Perkins
VP, Head of Cell & Genetic Medicines Discovery
Recent News
2025-08-14
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