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Tanaq Health · 5 hours ago

Bioinformatician II

Atlanta, GA

Full-time

Hybrid

Mid Level

4+ years exp

Tanaq Management Services (TMS) delivers professional, scientific, and technical services to federal agencies. They are seeking a highly motivated Bioinformatician II to support projects in public health, focusing on analyzing biological data and collaborating on vaccine development and infectious disease studies.

Management Consulting

No H1B

U.S. Citizen Only

Responsibilities

Assist in bioinformatics/computational biology projects including the creation and dissemination of NGS data

Support the development of novel and standardized bioinformatics analysis workflows (e.g., Nextflow, Snakemake, custom scripts/pipelines) for viral vaccine preventable diseases generated from next-generation sequencing platforms (e.g. Illumina, Element, Oxford Nanopore)

Support modification and enhancement of processes and tools of existing bioinformatic workflows to accommodate whole genome data

Provide technical assistance to integrate bioinformatics workflows with existing platforms in customer’s programs

Develop and/or use innovative methodologies and techniques; search, synthesize, and interpret information relevant to public health

Review and analyze studies and projects assessing major and/or sensitive public health issues in order to make recommendations for processes, procedures and/or policies related to public health programs, practices and research

Support in collecting and organizing information to help shape the strategic direction necessary for the customer to achieve its mission goals and objectives

Provide support with pertinent quality-related duties, including drafting and revision of standardized operating procedures, drafting and completion of method verifications and validations for next-generation sequencing methods and analysis pipelines

Assist in and lead projects in bioinformatics and computational biology

Provide data analysis support for sequencing requests through the Genome Sequence Lab

Conduct Bioinformatics Activities in support of several projects being undertaken in support of Global Polio Eradication Program

Perform assembly & Mapping activities, including genome assembly services for all sequencing platforms in the GSL (Sanger, Roche454, Illumina, Ion Torrent, MinION, and PacBio)

Provide single platform assembly using software packages to include CLCbio, Celera Assembler, MIRA, velvet, and BWA

Conduct Genomics analysis such as SNP/indel detection, gene structure comparisons, gene absence/presence determination, and protein sequence comparisons utilizing software packages such as kSNP, BLAST, and custom software

Perform variant detection techniques, including Amplicon or Deep Sequencing, to determine consensus sequences

Conduct Metagenomics techniques to identify species of microorganisms from an uncultured DNA sample utilizing BLAST/Megan, metagenefinder, QIIME, MG-RAST, and 16S databases utilizing RDP and Greengenes software packages

Provides legacy sequencing data retrieval

Analyze genetic sequencing data utilizing new methodologies or existing techniques that have been revised

Collaborate on genetic analysis projects and studies with internal and external partners

Assist laboratory scientists (with varying levels of computational expertise) in the design and implementation of bioinformatics tools that support the automation of data analysis, especially for next-generation sequencing data and large data sets

Advise senior scientists on applying a variety of bioinformatics analysis tools used to compare and categorize polio and picornavirus isolates and virus populations

Request NGS Sequencing for Illumina MiSeq and NovaSeq; PacBio RSII and Sequel; Oxford Nanopore MiniON

Qualification

R programmingBioinformatics pipelinesComparative genomicsMatlab applicationsNext-generation sequencingPublic health experienceAttention to detailTeam collaborationCommunication skillsOrganizational skills

Required

Minimum 4 years of experience in the capacity of a bioinformatician

Strong attention to detail

Ability to work independently and as part of a team in a fast-paced setting

Ability to work with a diverse interdisciplinary team

Excellent written and verbal communication skills

Effective organization skills

Ability to obtain government clearance

Must be legally authorized to work in the United States without the need for employer sponsorship, now or at any time in the future

Master's of Science degree in Bioinformatics, Computational Biology or related field with 4+ years of related experience required

Preferred

Experience with automation support; QMS & CLIA support; ELIMS integrations; Testing and curating new technologies, e.g., Nanopore; website development; communications and user experience preferred

Proficiency in R programming for statistical analysis preferred

Experience in Matlab applications preferred

Strong experience using applications such as BLAST/Megan, metagenefinder, QIIME, MG-RAST, and 16S databases such RDP and Greengenes preferred

Experience with de novo assembly and reference mapping preferred

Experience with RocheAVA, CLCbio, VIP, and VarScan software packages preferred

Ability to develop and implement bioinformatic pipelines to automate data analysis workflows preferred

Advanced experience with comparative genomics methods, including SNP/indel detection, gene structure comparisons, gene absence/presence determination, and protein sequence comparisons preferred

Previous experience in public health and molecular epidemiologic research, preferred

Experience working for the federal government or in a public health setting preferred

PhD in Bioinformatics, Computational Biology or related field preferred