R&D Partners · 15 hours ago
Bioinformatics - Manager
R&D Partners is seeking a Bioinformatics Manager who will play a crucial role in developing and applying AI models for target discovery and drug repurposing. The position involves designing and implementing AI-driven models, integrating large-scale datasets, and supporting hypothesis generation for novel targets and mechanisms.
Responsibilities
Design, train, and implement LLM- and GNN-based models to extract biological relationships from multi-modal data (omics, literature, chemistry, clinical)
Integrate knowledge graphs and structured biomedical databases to support hypothesis generation for novel targets and mechanisms
Apply AI-driven insights to identify, prioritize, and validate new drug targets and therapeutic hypotheses
Design in silico analyses to support mechanism-of-action elucidation, biomarker discovery, and patient stratification
Integrate large-scale datasets from public and proprietary sources (e.g., transcriptomics, proteomics, CRISPR screens, literature corpora)
Qualification
Required
PhD or MS with 5+ years of relevant experience in Computational Biology, Bioinformatics, Systems Biology, Computer Science, or a related discipline
Proven experience in target identification and translational discovery — from in silico analysis to preclinical validation
Strong understanding of molecular biology, pharmacology, and disease biology
Hands-on experience developing or applying AI/ML models to biological problems, especially LLMs, GNNs, or multi-modal integration architectures
Programming: Expert in Python (pandas, PyTorch, TensorFlow, scikit-learn, Hugging Face, PyTorch Geometric)
AI/ML Expertise: Proficiency in LLMs, GNNs, transformers, and model fine-tuning workflows
Bioinformatics Tools: Familiar with databases such as Ensembl, UniProt, ChEMBL, DrugBank, GEO, and OMIM
Data Integration: Experience with multi-omics data fusion and biomedical knowledge graphs
Preferred
Prior involvement in wet-lab collaboration (assay design, data interpretation, or experimental validation)
Company
R&D Partners
R&D Partners is a national staffing agency that specializes in scientific, clinical, and engineering positions.