Alexion Pharmaceuticals, Inc. · 3 hours ago
Computational Biologics Design Senior Scientist
Gaithersburg, Maryland, United States of America
Full-time
Onsite
Mid, Senior Level
$111K/yr - $166K/yrAlexion Pharmaceuticals, Inc. is seeking a Computational Biologics Design Senior Scientist to play a pivotal role in the delivery of novel biologics drugs for various diseases. This role involves leading in silico support on therapeutic projects, collaborating with scientists to establish structural analytics workflows, and driving innovative methods for biologic therapeutics design and optimization.
BiotechnologyHealth CareMedicalTherapeutics
Responsibilities
Lead the in silico support on pipeline therapeutic projects in collaboration with AZ stakeholders
Work collaboratively with data and drug discovery scientists to establish structural analytics workflows for biologics discovery
Contribute to the development of an end-to-end data analysis capability within Biologics Engineering team as part of a cross-functional team
Drive innovative structural, generative & machine learning methods for the design and optimisation of biologic therapeutics
Participate in strategic external collaborations
Demonstrate effective communication to translate complex concepts to non-experts in internal and external scientific meetings
Qualification
Required
PhD in relevant field (e.g. Structural Biology, Computer Science, Bioinformatics, Physics and Mathematics)
Knowledge of computational structural biology and demonstrated application of data analysis methods
Experience with structural modelling platforms (e.g. Schrodinger, Rosetta etc)
Familiarity with antibody discovery & optimisation, protein structures
Skilled in applying generative AI, Machine learning or deep learning to design and optimise proteins
Strong, professional communication skills and excellent attention to detail, capable of developing good working relationships with diverse individuals
Experience working within a team environment
Acts with integrity and does the right thing
Preferred
Knowledge of FAIR data principles
Experience with the analysis of large structural, sequence and experimental datasets
Benefits
Various incentives—an opportunity to receive short-term incentive bonuses
Equity-based awards for salaried roles
Commissions for sales roles
Qualified retirement programs
Paid time off (i.e., vacation, holiday, and leaves)
Health, dental, and vision coverage in accordance with the terms of the applicable plans
Company
Alexion Pharmaceuticals, Inc.
Alexion, AstraZeneca Rare Disease is focused on pioneering new possibilities for the rare disease community.
Founded in 1992
1001-5000 employees
H1B Sponsorship
Alexion Pharmaceuticals, Inc. has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (49)
2024 (57)
2023 (51)
2022 (29)
2021 (27)
2020 (17)
Funding
Current Stage
Public CompanyTotal Funding
$5.8M2020-12-12Acquired
1999-02-12Post Ipo Equity· $5.8M
1996-02-29IPO
Leadership Team
Frederic Chereau
SVP, Strategy and Business Development
Imran Shakur
Director, IRT and Technology Lead
Recent News
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2025-12-20
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