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Pfizer · 2 days ago

Associate Scientist, Assay Development

Cambridge, MA

Full-time

Onsite

New Grad, Entry Level

$60K/yr - $98K/yr

0+ years exp

Pfizer is dedicated to delivering breakthroughs that change patients’ lives, focusing on Research and Development to translate advanced science into impactful therapies and vaccines. The role involves establishing binding and functional assays to support the discovery of peptide and antibody-based therapeutics, collaborating with project teams, and analyzing data to drive programs forward.

BiotechnologyHealth CareMedicalPharmaceuticalPrecision Medicine

No H1B

Responsibilities

Develop assays to identify and characterize peptide, antibody and multispecific candidates to support programs across multiple therapeutic areas. Biochemical assay formats may include protein binding, competition and enzymatic cleavage assays. Cell based assays may include binding (FACS and ELISA), competition, cell signaling (NanoBiT, calcium flux, cAMP, phospho-protein HTRF/AlphaLISA, etc) and reporter gene assays using a variety of cell lines

Execute high-throughput screens using automated and semi-automated platforms and analyze results

Collaborate with project teams to establish screening strategies, interpret results, and make decisions to drive programs forward

Write protocols, maintain electronic lab notebook, and regularly review literature to maintain knowledge of scientific trends and new technologies

Qualification

Assay developmentBiochemical assaysCell-based assaysHigh-throughput screeningData analysisLiquid handling platformsHigh content imagingCoding experienceProblem solvingOrganizational skillsAttention to detailCommunication skills

Required

Bachelor's degree and 0-3 years of experience in molecular biology, biochemistry, cell biology or related discipline, along with a basic understanding of biologics drug discovery workflows

Demonstrated experience in assay development and troubleshooting with methods such as HTRF, ELISA/DELFIA, FACS, and cell-based functional assays focused on signaling, proliferation, or cytotoxicity

Demonstrated experience with plate-based assay formats and maintaining cell cultures is required

Track record of strong problem solving and organizational skills, attention to detail, and ability to multi-task

Strong written and oral communication skills