Novartis · 20 hours ago
Head, Translational Research and Biomarkers
Cambridge (USA)
Full-time
Onsite
Director/Executive
$186K/yr - $344K/yr
10+ years expNovartis Biomedical Research is seeking a visionary and execution-driven leader to head Translational and Biomarker Research within Disease Area X (DAx). This role will be pivotal in leading a team to design and execute preclinical and translational biomarker strategies across a diverse portfolio of drug discovery programs.
BiotechnologyHealth CareMedicalPharmaceuticalPrecision Medicine
Responsibilities
Define and drive the biomarker and translational research strategy for DAx, aligning with therapeutic area priorities in renal, liver, fibrosis, and exploratory indications
Lead the design, validation, and deployment of preclinical and clinical biomarker assays to support target engagement, pharmacodynamics, and patient stratification
Lead the histopathology and pathology team for target validation
Serve as a key organizational interface to help ensure end-to-end alignment of DAx program priorities
Establish and manage collaborations with academic institutions, consortia, and commercial sources to access patient samples and enable translational insights
Guide and mentor a high-performing team of scientists, fostering innovation, accountability, and scientific excellence
Qualification
Required
PhD, MD, or equivalent in biomedical sciences, pharmacology, molecular biology, or related discipline
Expertise in human translational data, multiomics profiling, and patient stratification approaches to enable biomarker discovery and validation
At least 10–15 years of experience in translational research, biomarker development, or related fields within pharma or biotech
Demonstrated prior leadership in preclinical and early clinical biomarker strategy
Proven track record in leading high-performing, multidisciplinary teams
Experience and comfort in leading and influencing across global sites
Strong ability to influencing matrixed environment
Preferred
Expertise in ex vivo, and in vitro systems for target validation, lead optimization, and biomarker development
Demonstrated experience in managing an exploratory portfolio of programs in multiple disease biologies
Strong strategic thinking and ability to align research goals with broader portfolio objectives
Ability to anticipate and shape internal and external shifts in the scientific and organizational landscape
Commitment to mentoring and developing talent, fostering a culture of curiosity, accountability, and scientific rigor
Benefits
Health, life and disability benefits
A 401(k) with company contribution and match
A variety of other benefits
A generous time off package including vacation, personal days, holidays and other leaves
Company
Novartis
Novartis is a pharmaceutical company that researches and develops medicines for serious diseases to improve and extend people's lives.
10001+ employees
H1B Sponsorship
Novartis has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (14)
2024 (27)
2023 (23)
2022 (27)
2021 (31)
2020 (25)
Funding
Current Stage
Public CompanyTotal Funding
$2.49BKey Investors
Bill & Melinda Gates Foundation
2024-06-19Post Ipo Debt· $2.49B
2018-02-14Grant· $6.5M
2000-05-19IPO
Leadership Team
Daniel Grant
Vice President & Global Program Head
John von Brachel
VP, Head of Content Lab
Recent News
MedCity News
2026-01-17
Labiotech UG
2026-01-17
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