Septerna · 4 hours ago
Senior Research Associate, Cell Culture (Contract role)
Septerna is a biotechnology company based in South San Francisco, CA, focused on developing life-changing medicines through innovative drug discovery technologies. The Senior Research Associate will contribute to the production and characterization of proteins, supporting drug discovery efforts for GPCR targets in a collaborative team environment.
BiotechnologyInformation TechnologyMedicalSoftware
Responsibilities
Perform as a hands-on cell culturist to help fully enable Septerna’s Native Complex™
Carry out continuous cell line maintenance primarily on Expi293 suspension cell lines, but also of insect cell lines when required
Perform transient transfections, stable pool selection, and cell line cryopreservation of Expi293 cell lines
Carry out small- and large-scale cell culture for production of recombinant proteins
Assist when needed with protein purification and protein-related assay technologies including ELISAs, SDS-PAGE, and DSF
Work collaboratively with Discovery Biology teams in ensuring proper prioritization and timelines of cell culture requests
Laboratory notebooking, data analysis and documentation
Qualification
Required
BS/MS with 2+ years of hands-on relevant experience in a biotechnology or pharmaceutical setting
1+ years demonstrated expertise in high-quality mammalian cell culture of suspension cell lines including HEK293, preferably using the Expi293 system
Experience in transient transfection, cell line maintenance, cell counting, stable pool selection, and cell cryopreservation
Ability to organize multiple projects to ensure delivery of reagents with appropriate prioritization and timelines
Demonstrated experience working collaboratively in a team-oriented environment
Clear and effective verbal and written communication skills
Preferred
Prior experience with ELISA assays and basic protein techniques (SDS-PAGE, Nanodrop, DSF) is desirable
Company
Septerna
Septerna is a biotech firm unlocking diverse drug discovery potential in G protein-coupled receptors across various diseases.
H1B Sponsorship
Septerna has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (3)
2022 (1)
Funding
Current Stage
Public CompanyTotal Funding
$250MKey Investors
RA Capital ManagementThird Rock Ventures
2024-10-25IPO
2023-09-12Acquired
2023-07-11Series B· $150M
Recent News
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