AstraZeneca · 2 months ago
Director, Country Operations Management
US - Boston - MA
Full-time
Hybrid
Director/Executive
$163K/yr - $244K/yr
7+ years expAstraZeneca is a leading biopharmaceutical company, and they are seeking a Director of Country Operations Management. This role is accountable for the execution of interventional Phase 2 and 3 clinical trials, leading a team to ensure operational trial milestones are met with quality and compliance.
BiopharmaBiotechnologyHealth CareMedicalPharmaceuticalPrecision Medicine
Responsibilities
Lead, manage, and develop a high-performing team of 8–10 direct reports, including local study project managers and clinical study administrators
Drive performance management, training, coaching, and career development aligned with business needs and individual development goals
Manage workload allocation, resource optimization, and team succession planning in partnership with senior leadership and HR
Provide input on compensation, bonus proposals, and promotions in collaboration with HR and the US Head of County Operations
Oversee the execution of Phase 2 & 3 interventional studies across site feasibility, start-up, recruitment, maintenance and close-out
Ensure trial milestones and deliverables are achieved with high quality and within agreed timelines
Robust oversight of site performance, study documentation, eTMF completeness, and regulatory compliance
Monitor key performance indicators (KPIs) and operational metrics across assigned TA to ensure quality and consistency
Identify and mitigate operational risks, issues, and roadblocks in collaboration with global study teams and local partners
Drive process improvements, standardization, and adoption of country-level best practices
Lead transformation and change initiatives to strengthen the local Clinical Operations Management (COM) function
Collaborate cross-functionally with local Medical Affairs, Regulatory, Legal, Development Quality, and other internal partners
Manage external vendor performance, including CROs and FSPs, ensuring alignment with clinical objectives and standards
Maintain effective communication pathways with global study teams, Start-Up Managers, Site Partnership functions, and CRA managers
Represent the local TA perspective in broader country strategy discussions
Qualification
Required
Bachelor's degree in life sciences or related field
Minimum 7 years of experience in clinical research, including significant exposure to Phase 2/3 interventional trials
At least 3 years of direct people management experience in clinical operations
Demonstrated success managing cross-functional and vendor relationships
Strong working knowledge of ICH-GCP, global regulatory requirements, and local trial execution environments
Proven ability to drive delivery across multiple concurrent studies in a fast-paced, matrixed environment
Excellent communication, influencing, and stakeholder management skills
Preferred
Previous experience as a field CRA
Experience in rare or ultra-rare disease trials, including pediatric or complex patient populations
Experience with U.S.-based studies and site management
Solid background in inspection readiness, risk mitigation, and continuous improvement
Benefits
Short-term incentive bonuses
Equity-based awards for salaried roles
Commissions for sales roles
Qualified retirement programs
Paid time off (i.e., vacation, holiday, and leaves)
Health, dental, and vision coverage
Company
AstraZeneca
AstraZeneca is a pharmaceutical company that discovers, develops, manufactures, and markets prescription medicines. It is a sub-organization of Investor.
10001+ employees
Funding
Current Stage
Public CompanyTotal Funding
$5.26B2024-07-30Post Ipo Debt· $1.51B
2023-02-28Post Ipo Debt· $2.25B
2023-02-24Post Ipo Debt· $1.5B
Leadership Team
Pascal Soriot
Executive Director and Chief Executive Officer
Aradhana Sarin
Group CFO and Executive Director
Recent News
Essential Business
2026-01-24
2026-01-23
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