Roche · 3 hours ago
Senior Scientist, Modeling and Simulations Scientist
South San Francisco
Full-time
Onsite
Mid, Senior Level
$102K/yr - $233K/yr
0+ years expRoche is a leading company in the pharmaceutical industry, and they are seeking a Senior Scientist in Modeling and Simulations. This role involves developing and applying mechanistic PKPD and systems pharmacology models to support drug development across various therapeutic areas.
BiotechnologyHealth CareHealth DiagnosticsOncologyPharmaceuticalPrecision Medicine
Responsibilities
Developing and applying mechanistic PKPD and systems pharmacology models in various therapeutic areas including oncology, immune & inflammatory disease, and other disease areas to support our drug development pipeline
Strategizing, planning executing, and reporting QSP and PKPD modeling activities, as well as to present work at cross-functional teams, department meetings, senior management review committees, regulatory interactions, and scientific conferences
Working in close partnership with other scientists in Modeling and Simulation, Clinical Pharmacology, Clinical Science, Informatics, Biostatistics, Preclinical and Translational PK, DMPK, Safety Assessment, Biomarker, Diagnostics, Regulatory, and other functions
Contributing to best practices on application of QSP and mechanistic PKPD in drug development
Presenting results at cross-functional teams, department meetings, review committees, and conferences
Adapting and thriving in an interactive, team-oriented culture
Qualification
Required
Ph.D in: chemical, biomedical, or other relevant engineering fields, pharmaceutical sciences, or a related discipline
Typical post-PhD experience requirements are roughly: Senior Scientist, ~0-3 years
Proficiency with PKPD and biological systems modeling approaches such as differential equations, logic, stochastic, agent-based, and/or other advanced mechanistic modeling approaches is essential as is proficiency with appropriate programming language and software (e.g., MATLAB/Simbiology, R, Python)
Excellent communication and interpersonal skills and the ability to work independently and effectively on cross-functional teams
Strong leadership skills and the ability to influence project team collaborators
Strong track record of external scientific presentation and publication, commensurate with hiring level
Benefits
Relocation benefits are available for this posting.
A discretionary annual bonus may be available based on individual and Company performance.
Company
Roche
Roche is a pharmaceutical and diagnostics company that offers medicines and diagnostic tests for various medical conditions and diseases.
10001+ employees
H1B Sponsorship
Roche has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (12)
2024 (9)
2023 (6)
2022 (2)
2021 (2)
Funding
Current Stage
Public CompanyTotal Funding
$7.79BKey Investors
SoftBankSCALE AINovartis
2021-08-04Post Ipo Equity· $5B
2020-12-07IPO
2020-05-06Post Ipo Equity· $0.5M
Leadership Team
Alan Hippe
Member of the Executive Board - Group CFO
Christine Bakan
Global Head and VP of Software and Bioinformatics, Next Generation Sequencing
Recent News
Labiotech UG
2026-01-17
2026-01-16
Company data provided by crunchbase