Roche · 5 hours ago
Senior Scientist
San Diego
Full-time
Onsite
Mid, Senior Level
$108K/yr - $201K/yr
2+ years expGenentech is a healthcare company that drives innovation to ensure everyone has access to healthcare. They are seeking a highly skilled and motivated Senior Scientist to join their Nucleic Acids Payload Engineering team, focusing on advancing a non-viral gene delivery platform and collaborating on drug discovery strategies.
BiotechnologyHealth CareHealth DiagnosticsOncologyPharmaceuticalPrecision Medicine
Responsibilities
Research Leadership: Advancing our fully non-viral gene delivery platform from the bench, driving ideation and testing of new approaches for non-viral DNA delivery. A highly creative scientist with a strong track record of rapidly generating and testing innovative ideas will thrive in this position
Interdisciplinary Collaboration: Collaborate closely with colleagues and internal experts across different teams in a highly cross-functional setting and ensure that data-driven insights are effectively translated into actionable drug discovery and clinical strategies
Translational Impact: Lead and execute high-quality, hypothesis-driven, and screening-based original research. Drive these projects to early feasibility and proof of concept decision points for potential integration into our in vivo gene and cell therapy pipelines, focusing on the treatment of rare blood disorders, autoimmune diseases, and cancer
Qualification
Required
Ph.D. in Molecular Biology, Cell Biology, Biochemistry or a closely related field
Minimum of two years of productive experience following their Ph.D., whether through postdoctoral training or in an industry setting
Strong record, demonstrated by high-impact publications, patents, and/or successful project transitions
Demonstrated expertise in non-viral gene delivery and/or nucleic acid manipulation
Experience with biochemical, molecular, and/or cell biology approaches
Highly collaborative spirit and excellent written and verbal communication skills
Exceptional creativity and a drive for innovation
Proven ability to work effectively with multidisciplinary teams
Preferred
Extensive expertise in advanced molecular cloning and nucleic acid manipulation techniques (e.g. Gibson assembly, SDM, Golden Gate cloning, mammalian expression vector design, IVT etc.)
Previous experience with nucleic acid shuttling and non-viral gene delivery systems
Experience with high-throughput, cell-based library screening and Next-Generation Sequencing (NGS)
Hands-on experience with functional molecular assays used for measuring success of transgene delivery/gene editing (e.g. via reporter assays, Western blot, qRT-PCR, ddPCR, or NGS)
Proficiency in the culture and genetic manipulation of cell lines and primary cells, including hepatocytes, T cells and monocytes
Must be a strong communicator
Benefits
Relocation benefits are available for this job posting.
A discretionary annual bonus may be available based on individual and Company performance.
Company
Roche
Roche is a pharmaceutical and diagnostics company that offers medicines and diagnostic tests for various medical conditions and diseases.
10001+ employees
H1B Sponsorship
Roche has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (12)
2024 (9)
2023 (6)
2022 (2)
2021 (2)
Funding
Current Stage
Public CompanyTotal Funding
$7.79BKey Investors
SoftBankSCALE AINovartis
2021-08-04Post Ipo Equity· $5B
2020-12-07IPO
2020-05-06Post Ipo Equity· $0.5M
Leadership Team
Alan Hippe
Member of the Executive Board - Group CFO
Christine Bakan
Global Head and VP of Software and Bioinformatics, Next Generation Sequencing
Recent News
Labiotech UG
2026-01-17
2026-01-16
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