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TakedaPharmaceutical Nordics AB · 22 hours ago

Research Senior Scientist, Lead Profiling

Boston, MA

Part-time

Hybrid

Senior Level

$137K/yr - $215K/yr

2+ years exp

TakedaPharmaceutical Nordics AB is a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. They are seeking a skilled Research Senior Scientist to join their Lead Profiling team, focusing on designing and running high throughput automated assays to support drug discovery for gastrointestinal, autoimmune, and inflammatory diseases.

Pharmaceuticals

Responsibilities

Design and execute pre-clinical pharmacology strategies on fully automated robotic platforms to support candidate selection, accelerating clinical translation of impactful therapies for patients with inflammatory and autoimmune disorders

Provide deep scientific expertise in the design and execution of miniaturized, high throughput assays for immunology/cellular pharmacology, acting as a subject matter expert across cross-functional teams

Leverage state-of-the-art automation to streamline complex biology screening workflows and manage data across GI2 programs, in close collaboration with Takeda scientists and external partners

Develop and implement fully-automated screening workflows to support multiple programs in the GI2 portfolio

Champion scientific integrity and rigor in data analysis, preparation, and interpretation of detailed protocols/SOPs

Collaborate effectively within a matrixed structure, clearly communicate results, challenges, and impact through presentations and discussions with broad audiences. Integrate data from cross-functional teams to drive decision-making

Think independently and creatively to explore novel drug discovery approaches to create therapies for patients suffering from immune driven disorders

Qualification

PhD in immunology/pharmacologyCell-based assay developmentHigh throughput data analysisState-of-the-art automationAssay miniaturizationLIMS systemsNovel small molecule developmentEngineering knowledgeProgramming knowledgeScientific literature awareness

Required

PhD degree in immunology/pharmacology with 2+ years industry experience, or MS with 8+ years' experience, or BS with 10+ years of relevant experience in pharmaceutical/ biotech R&D

Strong expertise and depth of knowledge in complex cell-based assay development and screening technologies (e.g., Flow cytometry, AlphaLISA, TR-FRET, ELISA and etc)

Extensive experience with state-of-the-art automation and assay miniaturization to streamline assay workflows

Significant experience leveraging high throughput data analysis platforms and LIMS systems for automated data analysis, QC and reporting

Proven experience in developing and/or evaluating novel small molecule and biologics

Stays current with emerging scientific literature, competitive landscapes, and innovative technologies