Humana · 2 days ago
Principal Applied AI Engineer
Louisville, KY
Full-time
Hybrid
Lead/Staff
$172K/yr - $237K/yr
10+ years expHumana Inc. is committed to putting health first and is seeking a Principal Applied AI Engineer to lead the development of AI-powered healthcare solutions. The role involves designing advanced generative AI systems, collaborating with cross-functional teams, and setting engineering standards to drive high-quality outcomes in healthcare delivery.
Health CareHealth InsuranceInsuranceVenture Capital
Responsibilities
Lead the design and build of advanced generative AI systems, spanning LLM-powered applications, multi-agent workflows, RAG, and domain-specific reasoning engines
Architect and own robust APIs and platform capabilities that bring AI to real business workflows at enterprise scale
Drive the engineering of high-quality data, feature, and evaluation pipelines that support reliable and continuously improving AI behavior
Partner with data scientists, platform engineers, and product leaders to transform conceptual ideas into resilient, testable, observable production systems
Set engineering standards and elevate team culture, emphasizing clarity, craftsmanship, iteration, and objective measures of excellence
Mentor other engineers and guide teams through complex technical decision-making
Serve as a thought leader on the practical application of generative AI technologies, emerging patterns, and their fit within our ecosystem
Champion observability, measurement, and operational excellence, ensuring deployed systems are trustworthy, maintainable, and high-performing
Stay at the forefront of AI/ML advancements and help the organization understand the right time, and the right way, to adopt new technologies
The successful candidate will help drive key business outcomes, including measurable improvements in healthcare delivery and member satisfaction
Qualification
Required
Bachelor's or Master's in Computer Science, Engineering, or a related quantitative field
10+ years of professional software or platform engineering experience
Deep expertise in Python, including building production services and shared libraries used by others
Hands-on experience with modern AI systems, including LLM integration, RAG, embeddings, and applied generative AI patterns
Strong background in machine learning engineering, including model deployment, monitoring, evaluation, and lifecycle management
Expert-level understanding of FastAPI, Flask, or similar frameworks, and REST/gRPC service design
Strong proficiency with cloud-native development on AWS, GCP, or Azure
Minimum 5 years of containerization and orchestration experience (Docker, Kubernetes)
Production experience with CI/CD pipelines, version control, and modern DevOps practices
Demonstrated ability to own large, ambiguous problems and deliver high-value, high-quality solutions
Preferred
Experience shaping engineering culture or influencing architectural direction across teams
Experience with generative AI tooling (e.g., LangChain, LlamaIndex, PydanticAI, or similar)
Strong understanding of deep learning frameworks (PyTorch, TensorFlow)
Experience with distributed systems (Akka, Flink, or similar)
Prior work building platforms rather than one-off applications
A track record of pragmatic decision-making, balancing innovation with maintainability and long-term value
Benefits
Medical, dental and vision benefits
401(k) retirement savings plan
Time off (including paid time off, company and personal holidays, volunteer time off, paid parental and caregiver leave)
Short-term and long-term disability
Life insurance
Company
Humana
Humana is a health insurance provider for individuals, families, and businesses.
10001+ employees
H1B Sponsorship
Humana has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (282)
2024 (246)
2023 (284)
2022 (274)
2021 (212)
2020 (84)
Funding
Current Stage
Public CompanyTotal Funding
$13.07B2025-05-30Post Ipo Debt· $5B
2025-03-03Post Ipo Debt· $1.25B
2024-03-11Post Ipo Debt· $2.25B
Leadership Team
Jim Rechtin
CEO and President
Nwando Olayiwola
Chief Health Equity Officer & Senior Vice President
Recent News
2026-01-16
2026-01-16
Company data provided by crunchbase