Crinetics Pharmaceuticals · 1 day ago
Senior Scientist 1, in Vivo Pharmacology
San Diego, CA
Full-time
Onsite
Mid, Senior Level
$127K/yr - $159K/yr
3+ years expCrinetics Pharmaceuticals is a pharmaceutical company based in San Diego, California, developing therapies for endocrine diseases. The Senior Scientist 1, In Vivo Pharmacology, will provide in vivo pharmacology support to Endocrine Discovery teams by designing, conducting, and interpreting experiments to evaluate the efficacy and toxicity of novel small molecules in animal models.
BiotechnologyHealth CarePharmaceuticalTherapeutics
Responsibilities
Design, conduct, and interpret in vivo experiments to evaluate the efficacy, pharmacokinetics, and safety of therapeutic candidate molecules in support of drug discovery programs with a focus on endocrine disease
Conceive of, research and develop new animal models of endocrine disease states
Demonstrate a high level of initiative to troubleshoot and accurately perform data analysis on in vivo studies
Participate in the exploration and evaluation of new targets in endocrinology
Analyze and present experimental data using Prism, Excel, MS Office or comparable software
Present findings to cross-functional internal groups, program team meetings, and at scientific conferences
Serve as an in vivo pharmacology lead for Endocrine Discovery programs
Manage outsourced studies and collaborations
Lead and supervise junior scientists
Contribute to scientific publications and in vivo pharmacology reports to support regulatory filings
Responsible for ensuring compliance with company established practices and procedures, including laboratory notebooks, computer files, quality and regulatory guidelines, and safety standards
Perform timely data verification and ensure accuracy for laboratory notebooks, protocols, reports, and regulatory filings
Willing to work some weekends and holidays as needed
Other duties as assigned
Qualification
Required
Ph.D. in Biology, Endocrinology, Behavioral Pharmacology, Physiology, Neuroscience, or related discipline with 3-5 years of relevant experience. Applicants with BS or MS degrees may apply but must demonstrate a minimum of 15 years of significant and relevant experience
Experience in designing and conducting rodent in vivo pharmacology studies
Experience working in the pharmaceutical industry
Hands on proficiency in rodent handling procedures and in vivo skills including dosing (IV, PO, SC), blood and tissue collection, necropsy, etc
Proficiency with basic surgical techniques
Must be independent and able to follow pre-established experimental designs, as well as develop new methods, protocols, and technologies based on existing literature
Able to effectively communicate and present summaries of research results to team members, and colleagues from other disciplines
Must have a strong work ethic and be enthusiastic for animal and laboratory work
Must be detail-oriented, punctual, reliable, and available on weekends when necessary
Strong written and verbal communication skills and ability to work effectively in a multidisciplinary team environment
Ability to work in a fast-paced environment and adapt to change
Preferred
Experience developing endocrinology in vivo models
Experience with non-GLP rodent toxicity studies
Experience managing direct reports
Benefits
Discretionary annual target bonus
Stock options
ESPP
401k match
Top-notch health insurance plans for employees (and their families) to include medical, dental, vision and basic life insurance
20 days of PTO
10 paid holidays
Winter company shutdown
Company
Crinetics Pharmaceuticals
Crinetics is a clinical-stage pharmaceutical company that develops therapies for people with rare endocrine diseases.
501-1000 employees
Funding
Current Stage
Public CompanyTotal Funding
$2BKey Investors
Frazier Healthcare PartnersNational Institutes of HealthPerceptive Advisors
2026-01-06Post Ipo Equity· $349.22M
2024-10-08Post Ipo Equity· $500M
2024-02-28Post Ipo Equity· $350M
Leadership Team
R. Scott Struthers
Founder, CEO
A
Alan S. Krasner
Chief Endocrinologist
Recent News
BioWorld Financial Watch
2026-01-15
2026-01-07
Company data provided by crunchbase