Washington University School of Medicine in St. Louis · 2 days ago
Senior Scientist (Computational) - Genetics
Washington University School of Medicine in St. Louis is seeking a Senior Scientist in Computational Genetics to work in the Cremins lab. This role involves overseeing computational infrastructure, developing algorithms for genomics data analysis, and mentoring junior analysts while contributing to interdisciplinary neuroscience research.
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Responsibilities
Collaborates on designing, conducting and reporting of research projects
Leads the process of monthly cleaning of servers and network attached storage across a 25 person laboratory to facilitate major long-term cost savings for the lab
Oversees the code development and data storage and accessibility needs of the laboratory toward discovery-based science across all genomics, imaging, and connectome data. Develops key algorithm in collaboration with other graduate students, postdocs, and scientists in the laboratory to advance the laboratories papers and discoveries
Trains to achieve mastery and excellence in code to call compartments, TADs, subTADs, loops in Hi-C/Micro-C/snm3c data, as well as in peak calling of Chip-seq, Cut&Run and Cut&Tag data. Establishes mastery codes in analyzing DNA damage repair, genomic instability data. Oversees trainees to ensure code and parameter selection implemented at highest standards
Creates algorithms to analyze data generated by their projects to create paper figures and make discoveries
Guides lab members to write and edit methods sections and figures for research papers where the analysis is used in the manuscript
Oversees junior computational scientists to ensure data is organized, managed, and curated on the cluster and servers to find biological patterns in a wide range of genetic and epigenetic sequencing and imaging data to facilitate the paper figures of lab members
Assists with grant preparation and reporting (editing, formatting, and facilitating stylistic and grammatical edits for lab’s annual grant progress reports, coordinating team members to arrange scientific content to meet grant progress deadline)
Prepares and submits papers on research
Assists PI in filling out of paperwork, including, but not limited to: dbGAP and ENCODE data portal approvals, Grant and University-related paperwork, yearly RRPR reports for every one of the lab’s grants - including coordinating with the subTeam members to get the content assembled
Oversees and writes established SOPs for data storage and movement onto GEO and NIH portals for public data accessibility
Trains new lab members on algorithms, bitbucket/github, data naming conventions, and GEO
Manages research project with other institutions and investigators
Performs other duties as assigned
Qualification
Required
Phd Or Terminal Degree Or Combination Of Education And Experience May Substitute For Minimum Education
No specific certification/professional license is required for this position
Postdoctoral (3 Years) Not Applicable
A driver's license is not required for this position
Preferred
Familiar with genomics assays and their computational pipelines, image processing (segmentation, spot calling, drift correction)
Exceptional commitment to upholding the collaborative ethos of the Cremins laboratory
Demonstrated ability to handle daily laboratory challenges with a dedication to the values of reconciliation, unity, mutual honor, and respect
Strong skills in verbal and written communication with a dedication to open transparent communication with mentors and peers
Strong orientation to detail with exceptional organizational skills
Benefits
Up to 22 days of vacation, 10 recognized holidays, and sick time.
Competitive health insurance packages with priority appointments and lower copays/coinsurance.
Take advantage of our free Metro transit U-Pass for eligible employees.
WashU provides eligible employees with a defined contribution (403(b)) Retirement Savings Plan, which combines employee contributions and university contributions starting at 7%.
Wellness challenges, annual health screenings, mental health resources, mindfulness programs and courses, employee assistance program (EAP), financial resources, access to dietitians, and more!
We offer 4 weeks of caregiver leave to bond with your new child.
Family care resources are also available for your continued childcare needs.
Need adult care? We’ve got you covered.
WashU covers the cost of tuition for you and your family, including dependent undergraduate-level college tuition up to 100% at WashU and 40% elsewhere after seven years with us.
Company
Washington University School of Medicine in St. Louis
WashU Medicine is a leader in improving human health throughout the world.
Funding
Current Stage
Late StageTotal Funding
$381MKey Investors
National Human Genome Research InstituteNational Cancer InstituteNational Institutes of Health
2025-01-21Grant
2024-12-16Grant· $10.8M
2023-05-11Grant· $22.5M
Leadership Team
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