Gossamer Bio · 1 week ago
Director/Senior Director Translational Bioinformatics
San Diego, California, United States
Full-time
Onsite
Director/Executive
$231K/yr - $272K/yr
10+ years expGossamer Bio is a biotech company seeking a visionary bioinformatics leader to join their Translational Science team. The successful candidate will lead the analysis of clinical biomarker data and drive innovation in translational bioinformatics, leveraging AI and multi-omics to enhance clinical development.
BiotechnologyHealth CareTherapeutics
Responsibilities
Lead the analysis of clinical biomarker data by developing and executing exploratory biomarker analysis plans (genetics, proteomics, RNA‑seq/single-cell, imaging), including pre-specification of hypotheses, endpoints, and statistical methodologies
Support clinical development programs by ensuring exploratory biomarker results, analyses and deliverables meet project timelines and regulatory-grade expectations, if applicable (data integrity, traceability, documentation)
Collaborate with interdisciplinary teams (Clinical, Research, Biostats) to perform (hands-on) and/or direct multi-omics data analyses and integration across various domains and apply best-in-class algorithms to directly address the motivating biological and clinical questions
Drive innovation by applying advanced bioinformatics, data science, machine learning (ML) and Artificial Intelligence (AI) methods to interrogate high-dimensional datasets, enabling mechanism-of-action insights, drug response biomarkers, and data-driven patient stratification
Effectively lead bioinformatics CRO relationships by developing work plans, fostering efficient communication and ensuring high-quality deliverables
Translate complex findings into clear narratives for clinical teams, governance and external audiences (posters/manuscripts)
Develop and scale the translational bioinformatics and AI platform and strategy, building a lean, high-impact team and external network to support future pipeline growth
Qualification
Required
Ph.D. (or equivalent experience) in computational biology, bioinformatics or biostatistics with 10+ years of biotech industry experience and a strong publication record in peer-reviewed journals
Expertise in next-generation sequencing algorithms, pipelines and applications (including single cell genomics)
Strong coding skills (eg. R, Python) with an excellent working knowledge of public bioinformatics databases, emerging technologies and reproducible research practices
Experience in pulmonary disease, fibrosis, inflammation, immunology and/or cardiovascular biology
Scientific curiosity and creativity, with an ability to identify questions that computational approaches can address, and the skills to develop solutions both independently and collaboratively
Demonstrated experience in evaluating and executing data science algorithms and machine learning/AI models
Proven ability to bridge computation and biology, with an entrepreneurial mindset and track record of driving innovation from concept to clinical impact
Strong communication (written and verbal), data presentation and visualization skills
Experience leading productive collaborative relationships, including remotely and across cultures
Comfortable communicating science and influencing strategic decisions at all levels
Preferred
A deep understanding of biology and the drivers of human disease would be a plus
Benefits
Medical, dental and vision insurance
401(k) and 401(k) matching
Long-term incentive plan
Disability plan
Vacation pay
Sick time
Holiday pay
Work, personal and family time off in accordance with the terms of the applicable plans
Company
Gossamer Bio
Gossamer Bio is a biopharmaceutical company focused on the discovery and development of novel and differentiated therapeutic products.
51-200 employees
H1B Sponsorship
Gossamer Bio has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (2)
2024 (2)
2023 (1)
2021 (4)
Funding
Current Stage
Public CompanyTotal Funding
$812MKey Investors
MidCap FinancialHillhouse Investment
2023-07-20Post Ipo Equity· $212M
2022-07-13Post Ipo Equity· $120M
2019-05-02Post Ipo Debt· $150M
Leadership Team
Faheem Hasnain
Founder, CEO and Chairman
Bryan Giraudo
Chief Financial Officer
Recent News
XOMA Royalty Corporation
2025-11-14
2025-11-08
2025-11-08
Company data provided by crunchbase