Foresite Labs · 1 week ago
Staff Engineer, Systems & DevOps
San Diego
Full-time
Hybrid
Senior Level, Lead/Staff
$175K/yr - $185K/yr
7+ years expForesite Labs is a venture-backed, stealth-stage biotechnology company focused on developing novel technologies for disease detection and management. They are seeking a Staff Engineer, Systems & DevOps to own the infrastructure and deployment foundations that support their engineering teams and ensure reliable systems across various environments.
BiopharmaBiotechnologyHealth CareMedical
Responsibilities
Design and maintain systems for software configuration, deployment, and upgrades
Own deployment workflows across development, test, and production environments
Support software running in test beds, lab environments, and experimental systems
Manage system configuration using best practices for reproducibility and traceability
Support on-device, on-prem, and cloud-adjacent deployments as required
Work closely with engineering teams to operationalize new software components
Design and implement centralized logging and metrics collection
Ensure logs and metrics are structured, searchable, and useful for debugging
Build and maintain internal tooling for log visualization, exploration, and analysis
Work with engineers to improve log quality, signal-to-noise ratio, and debuggability
Deploy and manage observability tooling such as:
Prometheus
Grafana
Loki
Cloud-based storage such as S3
Define logging and monitoring standards across services, test beds, and deployed systems
Support alerting, diagnostics, and post-mortem analysis for deployed systems
Build and maintain containerized environments for development and deployment
Define container build best practices and base images
Manage container runtimes and orchestration as appropriate to the system
Balance containerization with performance, debuggability, and operational simplicity
Administer and deeply understand Linux-based systems
Configure services, networking, storage, and security settings
Apply best practices for configuration management and system hardening
Debug system-level issues involving processes, filesystems, networking, and resource usage
Qualification
Required
BS/MS in Computer Science or Engineering
7+ years of experience in systems, DevOps, or infrastructure-focused software roles
Strong, hands-on Linux expertise (administration, debugging, performance)
Experience designing and operating CI/CD and build pipelines
Solid understanding of logging, metrics, and observability best practices
Experience deploying and maintaining containerized systems
Proficiency in at least one systems or scripting language: C/C++, Python, Shell scripting
Ability to read, debug, and support production C/C++ and Python applications
Experience integrating build systems (e.g., CMake, Make, Bazel, etc.) into CI pipelines
Experience interfacing with cloud-based infrastructures (AWS, Azure, GCP) - IAM, Tiered Storage, EKS/Kubernetes, Databases etc
Experience with logging and monitoring stacks such as: Prometheus/Grafana, Loki, S3 or similar object storage
Familiarity with cloud-adjacent tooling, even if systems are primarily on-prem or hybrid
Preferred
Experience supporting embedded or HPC-adjacent systems
Familiarity with configuration management tools or infrastructure-as-code concepts
Experience operating systems in regulated or reliability-sensitive environments
Experience supporting distributed systems or edge deployments
Benefits
Competitive compensation and equity package
Comprehensive benefits
Flexibility to support work-life integration
Company
Foresite Labs
Foresite Labs is a biotechnology company. It is a sub-organization of Foresite Capital.
11-50 employees
H1B Sponsorship
Foresite Labs has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (2)
2022 (1)
Funding
Current Stage
Early StageLeadership Team
Alex Blocker
CTO and Chief Data Scientist
Uplaksh Kumar
COO Foresite Labs and Venture Partner Foresite Capital
Recent News
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2026-01-02
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2025-11-19
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2025-11-17
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