AbbVie · 3 days ago
Senior Scientist I, Downstream Purification, PDS&T
Irvine, CA
Full-time
Onsite
Senior Level, Lead/Staff
$94K/yr - $178K/yr
8+ years expAbbVie is a company dedicated to discovering and delivering innovative medicines and solutions for serious health issues. The Senior Scientist I, Downstream Purification will apply scientific and engineering principles to develop robust manufacturing processes for biological products, supporting late-stage and commercial manufacturing.
BiotechnologyFinancial ServicesHealth CareMedicalPharmaceuticalVenture Capital
Responsibilities
Support late stage and commercial biologics manufacturing, technology transfer, process validation, investigations, troubleshooting, scale-up, and continuous improvement
Develop protein recovery and purification process that utilizes clarification, chromatography, and membrane filtration technologies. Provide deeper understanding of process performance using appropriate experimental and modeling tools
Design, execute and analyze experiments using a robust scale-down model for process characterization and continued process improvement of commercial biologics products
Leverage data science and advanced modeling to build digital platforms for data visualization and analysis
Support/ lead new product introduction into the manufacturing area, ensuring successful tech transfer, scale up and validation for the product
Support product investigations and non-conformances. Identify root causes and make scientific recommendations as to the acceptability and quality of affected product lots
Author and review relevant CMC sections of submissions and support agency inspections, inquiries and audits
Represent the PDS&T group in CMC program teams. Interact effectively with diverse groups within function and maintain strong working relationships with internal, global, and external collaborators
Qualification
Required
BS, MS, or PhD in Chemical Engineering, Biochemistry, Chemistry or closely related field with typically 10+ (BS), 8+ (MS) or 0+ (PhD) years of postdoc or industry related experience
Experience in areas of bioprocess development, process characterization, modeling, validation, regulatory submissions, and manufacturing support
Analytical thinker with excellent problem-solving skills and the ability to adapt to changing priorities and deadlines
Excellent communication, writing and presentation skills are required
Must have a 'results-oriented' work ethic and a positive 'can-do' attitude with a strong sense of urgency and self-motivated desire to achieve
Demonstrated knowledge of GMP and experience providing technical support in a GMP manufacturing environment
Demonstrated ability to collaborate effectively in a dynamic, cross-functional matrix environment
Benefits
Paid time off (vacation, holidays, sick)
Medical/dental/vision insurance
401(k)
Company
AbbVie
AbbVie is a biopharmaceutical company focused on immunology, oncology, neuroscience, virology, and aesthetics. It is a sub-organization of AbbVie.
10001+ employees
H1B Sponsorship
AbbVie has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (273)
2024 (190)
2023 (225)
2022 (284)
2021 (186)
2020 (186)
Funding
Current Stage
Public CompanyTotal Funding
$15B2024-02-27Post Ipo Debt· $15B
2023-03-08Post Ipo Equity· $0.25M
2012-12-20IPO
Leadership Team
Robert Michael
Chairman of the Board and Chief Executive Officer
Micah Bregman
Vice President, Global Strategy and Pipeline, Allergan Aesthetics
Recent News
2026-01-23
2026-01-20
2026-01-20
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