Pfizer · 22 hours ago
Postdoctoral Fellow, Quantitative Systems Pharmacology
Cambridge, MA
Full-time
Hybrid
New Grad
$65K/yr - $104K/yr
0+ years expPfizer is a leading biopharmaceutical company, and they are seeking a highly motivated postdoctoral fellow to develop and analyze mechanistic quantitative systems pharmacology models of rheumatoid arthritis. The role involves creating quantitative tools to inform target selection, guide the development of novel therapeutics, and support clinical trial optimization while collaborating with a dynamic interdisciplinary team.
BiotechnologyHealth CareMedicalPharmaceuticalPrecision Medicine
No H1B
Responsibilities
Applying modeling and simulation approaches to predict the effects of novel therapies and/or target combinations
Identifying and integrating relevant data sources (preclinical, systems immunology, and clinical) for model development, calibration, and validation
Designing nonclinical experiments to generate data for model validation and hypothesis testing
Communicating modeling results and strategic insights effectively to scientists from both quantitative and non-quantitative disciplines
Serving as primary author on scientific publications and presenting research findings at internal and external scientific meetings
Qualification
Required
Ph.D. (0-2 years) in Applied Mathematics, Mathematical Biology, Chemical Engineering, Biomedical Engineering, Physics, Pharmaceutical Sciences, Pharmacology, Immunology, or related discipline with strong numerical components focusing on mathematical modeling and simulation
Training or previous experience in building QSP or differential-equation-based models of biological or physiological pathways/systems is required
No more than 2 years of post-degree experience
Willingness to make a minimum 2-year commitment
Successful record of scientific accomplishments evidenced by scientific publications and/or presentations with at least one first-author publication in a peer-reviewed journal
Preferred
Understanding of theory, principles, and statistical aspects of mathematical modeling and simulation, including parameter estimation techniques
In-depth understanding of ordinary differential equations (ODEs) and how these can be applied in the development of complex models of biological pathways and systems
In-depth, hands-on knowledge of modeling and simulation software (MATLAB or Julia preferred)
Keen interest in learning new areas of biology and building on a solid foundation of quantitative and computational skills
Self-directed with ability to work independently
Ability to perform as a team player and collaborate cross functionally in multiple disciplines
Excellent communication and writing skills
Benefits
401(k) plan with Pfizer Matching Contributions
Additional Pfizer Retirement Savings Contribution
Paid vacation
Holiday and personal days
Paid caregiver/parental and medical leave
Health benefits to include medical, prescription drug, dental and vision coverage
Company
Pfizer
Pfizer is a biopharmaceutical company that discovers, develops, and delivers medicines and vaccines.
10001+ employees
Funding
Current Stage
Public CompanyTotal Funding
$38BKey Investors
Starboard Value
2025-11-21Post Ipo Debt· $6B
2024-10-07Post Ipo Equity· $1B
2023-05-16Post Ipo Debt· $31B
Leadership Team
Albert Bourla
Chief Executive Officer
Ian Read
Chief Executive Officer
Recent News
2026-01-22
Maryland Daily Record
2026-01-22
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