AnteAGE · 2 days ago
Scientist I/II – Lipid Nanoparticle Formulation & Process Development
Irvine, CA
Full-time
Onsite
Mid, Senior Level
$95K/yr - $120K/yr
2+ years expCellese Inc. is a leader in regenerative science and advanced skincare, developing cutting-edge cosmeceuticals. They are seeking a Scientist I/II to design, optimize, and scale lipid nanoparticle formulations for skincare and regenerative applications, contributing to the development of novel delivery platforms and supporting both internal R&D and external collaborations.
BeautyManufacturingRetail
No H1B
Responsibilities
Research, develop, and optimize lipid nanoparticle formulations for skincare and regenerative ingredient delivery
Design and execute experiments using Quality by Design (QbD) and Design of Experiments (DoE) approaches to establish critical process parameters (CPPs)
Manufacture nanoparticles using microfluidic mixers and downstream purification (TFF) methods
Conduct analytical characterization (NTA, zeta potential, HPLC/UPLC, Ribogreen, stability testing) to define and monitor critical quality attributes (CQAs)
Support pilot-scale production, lyophilization, and fill/finish development
Partner with biology teams to test formulations in vitro and leverage data for iterative improvement
Prepare SOPs, batch records, development reports, and technology transfer packages for cross-functional use
Present findings internally and externally, contributing to both tactical development and strategic innovation discussions
Qualification
Required
PhD in Chemical Engineering, Bioengineering, Pharmaceutical Sciences, Chemistry, Biology, or related field with 2+ years relevant experience; OR M.S. with 4+ years; OR B.S. with 6+ years
Hands-on expertise in lipid nanoparticle formulation and process development
Strong knowledge of microfluidic nanoparticle assembly, lipid self-assembly, and TFF purification
Practical experience with analytical methods (NTA, HPLC/UPLC, SEC, IEX, IP-RP, fluorescence assays)
Familiarity with in-process controls, stability testing, and data/statistical analysis
Ability to independently design, troubleshoot, and document experiments
Preferred
Knowledge of exosome or hybrid EV–LNP technologies
Background in skin or hair biology models
Understanding of cGMP expectations and regulatory considerations for nanoparticle-based products
Familiarity with statistical software for DoE and process optimization
Benefits
Health, dental, vision, and life insurance
401(k) with company match
2 weeks PTO plus 12 holidays
Quarterly team events
Catered lunches
Casual culture
Complimentary company skincare products
Company
AnteAGE
AnteAGE manufacturers sell, and retailers skincare products.
51-200 employees
Funding
Current Stage
Growth StageCompany data provided by crunchbase