Talus Bio · 22 hours ago
Research Associate II, Biology / Drug Discovery
Seattle,WA,US
Full-time
Onsite
Entry, Mid Level
$70K/yr - $85K/yr
1+ years expTalus Bio is a venture-backed early-stage biotechnology company focused on developing innovative therapies for incurable cancers. The Research Associate II will support drug discovery programs targeting transcription factors implicated in cancer, working closely with a multidisciplinary team to design, execute, and analyze experiments to advance lead compounds through preclinical stages.
Artificial Intelligence (AI)BiotechnologyHealth CareTherapeutics
Responsibilities
Conduct laboratory experiments to support the discovery and characterization of small molecules targeting transcription factors in cancer
Perform cell-based assays (e.g., cell viability, apoptosis, and reporter assays) to evaluate compound efficacy and mechanistic effects on transcription factors
Utilize molecular biology techniques (e.g., PCR, RT-qPCR, CRISPR, RNAi) to analyze gene expression and validate targets
Contribute to the design, optimization, and execution of assays for high-throughput screening and compound profiling
Maintain detailed and accurate laboratory notebooks and records in compliance with company policies
Collaborate effectively with team members to solve technical challenges and streamline workflows
Stay current on relevant literature and emerging technologies in cancer biology, transcription factor research, and drug discovery
Ability to multitask and advance multiple projects at different stages simultaneously from assay development to compound screening
Maintain complete, timely, and accurate records of all experiments performed, including experimental design, procedures, and data analysis
Analyze/interpret experimental data and communicate the results and recommendations to other team members (oral and written formats)
Must be highly-motivated and able to work independently
Qualification
Required
Bachelor's degree in Molecular Biology, Biochemistry, Cancer Biology, or a related field
2 years of hands-on research experience running RT-qPCR assays including selection and custom-design of oligos. Experience with cell culture techniques and handling of cancer cell lines
Alternately: Master's degree with at least 1 year of experience in a similar role
Preferred
Prior experience in drug discovery, especially with transcription factor targets in cancer
Familiarity with high-throughput screening assays and/or experience in hit-to-lead workflows
Familiarity with cell-based assays (e.g., cell viability, reporter assays for evaluating compound effects
Working knowledge of data analysis software (e.g., GraphPad Prism, Excel) and basic statistical methods
Benefits
Medical/dental/vision insurance coverage with 100% company-paid premiums for employees and 50% company-paid for dependents
$124/month commuter and transportation reimbursement program
401(k) plan with a 4% Talus Bio contribution (regardless of employee contribution)
Basic Life and AD&D insurance coverage with 100% company-paid premiums
Short- and Long-Term Disability insurance coverage with 100% company-paid premiums
Paid sick leave (52 hours/year)
4 weeks of paid time off PLUS a paid end-of-year shutdown between Christmas Day and New Year's day
10 paid holidays
Weekly meals, snacks, and drinks
Flexible working hours
Flexible working environment and schedule
Yearly company retreat and quarterly company events
Company
Talus Bio
Talus Bio is a drug discovery biotech company that develops drugs targeting undruggable transcription factors using AI.
11-50 employees
Funding
Current Stage
Early StageTotal Funding
$27.78MKey Investors
Two Bear CapitalNCATSNational Institute of Health
2024-08-20Seed· $11.2M
2024-02-01Grant· $2M
2023-09-14Grant· $0.71M
Leadership Team
Alex Federation
Co-Founder, CEO
Lindsay Pino
Co-Founder and CTO
Recent News
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