Absci · 22 hours ago
Senior Scientist, Immunology & Bioassays
Vancouver, WA
Full-time
Onsite
Senior Level
$130K/yr - $145K/yr
5+ years expAbsci is a clinical-stage biotechnology company advancing novel therapeutics using generative AI. They are seeking a highly motivated scientist to join their Pharmacology and Bioassays team, responsible for developing and executing in vitro and ex vivo assays to support drug development.
Artificial Intelligence (AI)BiopharmaBiotechnologyLife Science
Responsibilities
Design, develop, and execute preclinical in vitro and ex vivo cell-based assays to advance therapeutic programs and support target validation, MOA elucidation, and lead characterization
Analyze and interpret complex experimental datasets to define functional activity, mechanistic insight, and biological relevance of therapeutic candidates
Identify, evaluate, and implement new assay models, technologies, and experimental approaches to strengthen disease-relevant biology and assay capabilities
Serve as an immunology subject matter expert, integrating literature, experimental data, and disease biology to support project decisions and milestone advancement
Independently troubleshoot and optimize complex assays, applying scientific judgment to resolve technical and biological challenges
Contribute to the development and expansion of advanced in vitro and ex vivo research capabilities within the Pharmacology & Bioassays team
Author and review SOPs, study reports, and scientific presentations to ensure clarity, rigor, and reproducibility
Qualification
Required
Ph.D. or equivalent advanced degree in Pharmacology, Immunology/Inflammation, Physiology, cell biology, or related disciplines with at least 5+ years of post-PhD academic and/or industry experience in immunology, immune-mediated inflammatory diseases, or related field, establishing direct experimental experience with the complex biology of inflammatory diseases
Extensive experience with flow-based in-depth characterization of immune cell populations in blood and tissue samples
Experience with cell-based assays, ELISA, MSD, qPCR, microscopy, histology/pathology (e.g. IF/IHC/ISH)
Demonstrated expertise with complex 2D/3D functional cell-based and tissue-based assays to investigate disease biology and PK/PD relationship
Experience with leveraging complex data sets to characterize and establish a drug's therapeutic mechanisms of action
Ability to be hands-on and work in the lab, write protocols, and execute studies leveraging Absci's in-house capabilities
Experience working with project/research teams with functional responsibility to propose strategy, analyze, interpret, and present complex data to inform decisions
Ability to collaborate in writing protocols and reports
Outstanding communication skills with demonstrated ability to make effective presentations in a broad range of settings
Preferred
Demonstrated record of leveraging in vitro/ex-vivo pharmacology models to explore antibody-based drug discovery
Experience with therapeutics programs leading to drug candidate nomination in one or more of the following therapeutic areas: oncology, immunology/inflammation, metabolic diseases
Experience authoring study protocols, reports, and/or regulatory documents, including IBs, IND filings, and/or NDAs
Experience working with complex patient-derived cell-based 2D/3D culture systems or ex vivo tissue models
Ability to independently generate, analyze, and interpret multi-omics data sets
Strong statistical analysis skills and an ability to articulate findings and make recommendations from complex study results
Experience mentoring scientists, leading cross-functional project teams, and a track record of successful management of external teams
Experience working with vendors and CROs to execute studies, analyze data, and generate reports promptly
Benefits
Medical
Dental
Vision insurance
Unlimited vacation
Parental leave
Employee assistance program
Voluntary life and disability insurance
Annual bonus potential
401(k) with a generous company match
Company
Absci
Absci is the drug & target discovery company harnessing deep learning AI & synthetic biology to expand the therapeutic potential of proteins
51-200 employees
H1B Sponsorship
Absci has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (4)
2024 (3)
2023 (1)
2022 (3)
2021 (2)
2020 (2)
Funding
Current Stage
Public CompanyTotal Funding
$394.26MKey Investors
AMDMerck Global Health Innovation FundCasdin Capital
2025-07-24Post Ipo Equity· $50M
2025-01-08Post Ipo Equity· $20M
2024-02-27Post Ipo Equity· $86.4M
Leadership Team
Sean McClain
Founder & CEO
Andreas Busch
Chief Innovation Officer
Recent News
2025-12-12
2025-12-11
2025-12-11
Company data provided by crunchbase