Ionis Pharmaceuticals, Inc. · 13 hours ago
Senior Research Associate / Assistant Director, ADQC
Carlsbad, CA
Full-time
Hybrid
Senior Level, Lead/Staff, Director/Executive
$80K/yr - $195K/yr
5+ years expIonis Pharmaceuticals, Inc. is a leader in RNA-targeted medicines, headquartered in Carlsbad, California. They are seeking an experienced analytical chemist for their Analytical Development & Quality Control group at the Senior Research Associate, Senior Scientist, or Assistant Director level, focusing on oligonucleotide therapeutic development projects and managing analytical activities.
BiotechnologyHealth CareMedicalPharmaceutical
Responsibilities
Manage the analytical activities for oligonucleotide therapeutic development projects
Coordinate and execute testing of drug substance intermediate, drug substance, and drug product samples for release and stability studies
Manage outsourced analytical activities at external contract labs
Conduct analytical investigations
Develop and optimize analytical methods
Develop drug substance specifications ensuring efficient integration across Chemistry, Manufacturing, and Controls (CMC) and other relevant disciplines such as Clinical and Toxicology
Design and execute method validation and method transfer protocols
Author scientific reports and portions of the CMC section of regulatory filings
Present at internal and cross-functional scientific meetings
Qualification
Required
BS or MS with at least 5 years (Sr. Research Associate) or 8 years (Assistant Director) of industry experience in Analytical Chemistry or related discipline
Ph.D. with at least 2 years (Sr. Scientist) or 8 years (Assistant Director) of industry experience in Analytical Chemistry or a related discipline
Skilled in operating LC-MS, HPLC, and GC for the analysis of drug substance and drug product samples
Good understanding of the drug development process
Practical knowledge of GMP requirements, with hands-on GMP experience preferred
Good understanding of ICH and FDA method validation guidelines, including phase-appropriate strategies
Ability to problem solve, manage priorities and maintain aggressive timelines for multiple projects
Ability to work productively and independently within a team or matrix environment
Excellent written and verbal communication skills
Preferred
Hands-on GMP experience
Benefits
Ionis offers an excellent benefits package!
Company
Ionis Pharmaceuticals, Inc.
For three decades, Ionis has invented medicines that bring better futures to people with serious diseases.
501-1000 employees
H1B Sponsorship
Ionis Pharmaceuticals, Inc. has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (8)
2024 (5)
2023 (3)
2022 (5)
2021 (5)
2020 (1)
Funding
Current Stage
Public CompanyTotal Funding
$2.45B2025-11-13Post Ipo Debt· $700M
2024-09-09Post Ipo Equity· $500.3M
2023-06-06Post Ipo Debt· $500M
Leadership Team
Brett P. Monia
Chief Executive Officer
Eric Bastings
Senior Vice President, Development Strategy
Recent News
Labiotech UG
2026-01-22
Business Wire
2026-01-22
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