United Therapeutics Corporation · 5 hours ago
Research Associate I - HLA/SLA
Morrisville, NC
Full-time
Onsite
Entry Level
1+ years expUnited Therapeutics Corporation is a publicly-traded biotech company focused on developing novel pharmaceutical therapies and technologies for transplantable organs. The Research Associate I - HLA/SLA is responsible for performing immunogenetics testing to support xenotransplantation research and regulatory milestones, collaborating with teams to optimize assays and ensure high-quality data.
BiotechnologyPharmaceuticalTherapeutics
Responsibilities
Perform routine and complex immunogenetics testing (e.g., PCR-based typing, Next-Generation Sequencing, Luminex/Intelliflex assays) on human and porcine samples
Assist in development, validation, and optimization of assays for histocompatibility testing (HLA/SLA)
Isolate, culture, and prepare PBMCs, endothelial cells, and other relevant cell populations for compatibility testing
Troubleshoot technical issues, maintain assay performance, and document deviations or corrective actions
Maintain and calibrate laboratory equipment, ensuring readiness for regulated testing and audits
Contribute to scientific manuscripts, abstracts, and conference presentations
Stay current with relevant literature, technologies, and regulatory guidelines in HLA/SLA testing and xenotransplantation research
Document all laboratory activities in compliance with GLP, CLIA, CAP, EFI, and/or FDA regulatory requirements
Assist in writing, reviewing, and updating SOPs, validation protocols, and quality records
Participate in internal audits, CAP inspections, and regulatory reviews
Assist in training junior staff and collaborators in proper laboratory techniques and assay workflows
Collaborate with clinicians and R&D scientists to design experiments and refine donor–recipient matching strategies
Qualification
Required
Bachelor's Degree in a related field
1+ years of histocompatibility experience
Proficiency in laboratory techniques (pipetting, cell handling, molecular assays, flow cytometry)
Capacity to participate in multiple projects with competing timelines in a fast-paced research and clinical environment
Effective problem-solving skills to troubleshoot assay failures and identify root causes
Competence with electronic laboratory notebooks (ELN), LIMS systems, and basic bioinformatics workflows
Ability to work flexible hours including evenings and weekends on an ad hoc basis
Preferred
ABHI - American Board of Histocompatibility and Immunogenetics Certified Histocompatibility Technologist (CHT) or Supervisor (CHS)
Strong understanding of immunogenetics, including HLA and SLA systems, antigen presentation, and transplant immunology
Familiarity with xenotransplantation models, including swine genetics, immunobiology, and donor-recipient matching considerations
Working knowledge of cell culture techniques, including PBMC and endothelial cell isolation and maintenance
Knowledge of crossmatch methodologies (CDC, flow cytometry) and interpretation of cytotoxicity/antibody binding data
Excellent technical documentation skills for SOP writing, assay reports, and regulatory submissions
Benefits
Medical / dental / vision / prescription coverage
Employee wellness resources
Savings plans (401k and ESPP)
Paid time off & paid parental leave benefits
Disability benefits
Company
United Therapeutics Corporation
Founded to find a cure for a daughter’s rare disease, United Therapeutics is a biotechnology company transforming care for people with chronic and life-threatening conditions.
1001-5000 employees
H1B Sponsorship
United Therapeutics Corporation has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (10)
2024 (13)
2023 (8)
2022 (6)
2021 (9)
2020 (4)
Funding
Current Stage
Public CompanyTotal Funding
unknown1999-06-17IPO
Leadership Team
Hamlet Bonilla Evertsz
Senior Network Engineer
Recent News
2026-01-15
2026-01-09
2025-12-29
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