Eurofins PSS Insourcing Solutions · 1 day ago
Downstream Development Engineer – Pilot Operations
Lexington, MA
Full-time
Onsite
Entry, Mid Level
$30/hr - $34/hr
2+ years expEurofins PSS Insourcing Solutions is a global leader in analytical testing services across various industries. The Downstream Development Engineer will support pilot lab operations, executing both routine and complex operations, and collaborating with teams to ensure effective tech transfer and process improvements.
Biotechnology
No H1B
Responsibilities
Execute non-GMP Downstream Purification operations at pilot scale (50-1000L) to support new product development, material supply, process improvements, and demonstration runs for various programs across the whole development lifecycle, including post-launch commercial processes
Partner with other process development and manufacturing sciences teams to troubleshoot and resolve process challenges and support large-scale studies
Coordinate and manage critical process details, including long-lead item tracking, sample planning, material ordering, and vendor interactions
Independently record, analyze, and interpret process data, identifying patterns and trends
Present findings and technical issues at departmental and project meetings, proposing solutions and implementing corrective actions under supervision
Contribute to pilot-scale procedures and documentation
Support global tech transfers
Support the authoring of technical reports, protocols, and internal presentations. Assist team members with scientific publications, external abstracts, and conference presentations as required
Evaluate and integrate novel pilot-scale technologies and digital tools to establish a versatile platform supporting multiple bioprocesses
Drive continuous improvement through the adoption of innovative solutions to enhance efficiency, data analytics, and operational performance
Qualification
Required
Bachelor's degree in Chemistry, Biology, Pharmacy, Engineering, or related pharmaceutical science with 2+ years of relevant industry experience, OR a Master's degree in related fields (industry experience preferred but not required)
Experience with downstream purification processes is required
Hands-on experience with downstream activities such as chromatography, ultrafiltration/diafiltration (UF/DF), tangential flow filtration (TFF), and depth/sterile filtration
Experience supporting non‑GMP batches within an R&D Pilot Plant environment operating at the 50–1000 L bioreactor scale (interface between lab‑scale and full‑scale GMP manufacturing)
Strong analytical and problem‑solving abilities; able to troubleshoot technical issues using data and scientific judgment
Effective collaborator with the ability to work well within cross‑functional teams
Clear and concise communicator with strong documentation practices and the ability to escalate issues appropriately
Strong organizational skills with the ability to manage multiple priorities and meet deadlines
Proficient in operating and maintaining relevant laboratory equipment; familiarity with upstream processes is a plus
Ability to wear required PPE (safety glasses/goggles, gloves, safety shoes)
Ability to lift, push, or pull up to 25 lbs, stand for up to 4 hours, and climb ladders/work platforms or bend/stoop to inspect equipment
Must be authorized to work in the United States indefinitely without restriction or sponsorship
Preferred
Experience with AKTA chromatography systems and Unicorn software preferred
Benefits
Excellent full-time benefits, including comprehensive medical coverage, dental, and vision options
Life and disability insurance
401(k) with company match
Paid vacation and holidays
Yearly goal-based bonus & eligibility for merit-based increases
Company
Eurofins PSS Insourcing Solutions
Welcome to Eurofins Professional Scientific Services® (PSS), where we redefine industry norms in insourcing solutions, creating unparalleled value for both our dedicated employees and esteemed clients.
1001-5000 employees
Funding
Current Stage
Late StageCompany data provided by crunchbase