CHEManager International · 1 day ago
Post Doctoral RA - Synthetic Biology and Biosensor Design
Richland, WA
Full-time
Onsite
New Grad, Entry Level
$69K/yr - $119K/yrPacific Northwest National Laboratory (PNNL) is a world-class research institution focused on scientific research and innovation. They are seeking a motivated researcher with expertise in biosensors and strain engineering to develop automated phenotyping and genome editing workflows for biofuels and bioproducts.
Responsibilities
Lead efforts to develop, optimize, and validate genetically encoded and/or synthetic biosensors that report on cellular states, metabolic fluxes, and target molecule production in microbial, fungal, and algal systems
Design, develop, and implement high-throughput automated workflows for the EMSL User Program
Integrate biosensor-based phenotyping with high-resolution, single-cell analyses and multi-modal techniques to uncover genetic drivers of phenotypic traits, elucidate protein function, and guide iterative strain improvement
Work within a multi-researcher, interdisciplinary team to engineer strains with enhanced traits using genome editing and synthetic biology tools
Refine biosensor designs and phenotyping strategies across cell-free, in vitro, and in vivo contexts; integrate experimental datasets using bioinformatics and molecular tools; and contribute to scientific publications, user-facing protocols, and technical reports that highlight new biosensor technologies and their applications
Collaborate with interdisciplinary and multi-institutional teams, including EMSL users who will leverage these biosensor-enabled platforms, to achieve research goals
Ensure adherence to laboratory safety and compliance standards
Qualification
Required
Candidates must have received a PhD within the past five years (60 months) or within the next 8 months from an accredited college or university
Preferred
Ph.D. in microbiology, bioengineering, microbial genetics, chemical engineering, or a related field
Demonstrated expertise in strain development, lab automation, and genetic engineering
The ideal candidate will have a Ph.D. in microbiology, synthetic biology, bioengineering, or a related field, with demonstrated expertise in biosensor design, development, and application in vivo and in vitro
Experience developing and deploying genetically encoded or synthetic biosensors in microbial, fungal, and/or algal systems, as well as using cell-free expression or metabolic platforms to prototype and optimize biosensors, is highly desirable
Candidates should also have a strong background in strain engineering and genome editing tools (e.g., CRISPR/Cas, CRISPRa/i), and in integrating biosensor readouts with high-throughput phenotyping workflows and automated cultivation systems
Proficiency in applying multi-modal phenotyping techniques (e.g., transcriptomics, proteomics, metabolomics, single-cell methods) to link genetic drivers to phenotypic traits, and in using bioinformatics tools to analyze and integrate these datasets, is preferred
A strong record of peer-reviewed publications, successful collaboration within interdisciplinary and multi-institutional teams, and experience supporting user or collaborative research programs are all advantageous
The successful candidate will interact with other staff and participate in team-based, collaborative research within PNNL and with external organizations. Therefore, strong written, oral, and interpersonal communication skills are essential for independently carrying out initial analysis of experimental data and presenting summaries to project managers and staff
Benefits
Medical insurance
Dental insurance
Vision insurance
Robust telehealth care options
Several mental health benefits
Free wellness coaching
Health savings account
Flexible spending accounts
Basic life insurance
Disability insurance
Employee assistance program
Business travel insurance
Tuition assistance
Relocation
Backup childcare
Legal benefits
Supplemental parental bonding leave
Surrogacy and adoption assistance
Fertility support
Company-funded pension plan
401 (k) savings plan with company match
Up to 120 vacation hours per year
Ten paid holidays per year
Company
CHEManager International
Wiley’s leading media brand providing first-hand information on the global chemical, life science and process industries
201-500 employees
Funding
Current Stage
Growth StageCompany data provided by crunchbase